Results 61 to 70 of about 3,489,699 (322)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

PARTISIPASI MAHASISWA GEOGRAFI TERHADAP PELESTARIAN LINGKUNGAN MELALUI MODEL PEMBELAJARAN PROJECT BASED LEARNING DALAM KAJIAN KOTA HIJAU (GREEN CITIES)

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2017
Human activities such as the conversion of agricultural land to unsustainable development, forest burning, environmental pollution and environmental indifference are factors of environmental damage.
Noviani Nurkolis, Sumarmi Sumarmi, I Komang Astina   +2 more
doaj   +1 more source

Efektivitas Project Based Learning (Pjbl) Berbasis Transfer Nilai-nilai Pancasila dalam Meningkatkan Keterampilan Menulis Buku Ajar Pkn SD Bagi Mahasiswa Pgsd Umc [PDF]

, 2018
Tujuan penelitian ini adalah meningkatkan keterampilan menulis mahasiswa PGSD UMC dalam membuat bukuajar PKn SD kelas 5 melalui modelpembelajaran proyek atau Poject Based Learning (PjBL) berbasis transfer nilai-nilai Pancasila. Penelitian ini menggunakan
Dianasari, D. (Dianasari), Hanikah, H. (Hanikah), Setiana, D. (Diana)   +2 more
core  

Project based learning on industrial informatics: applying IoT to urban garden [PDF]

, 2018
Copyright (c) 2018 IEEEThe fast evolution of technologies forces teachers to trade content off for self-learning. PBL is one of the best ways to promote self-learning and simultaneously boost motivation.
Hormigo-Aguilar, Javier, Rodriguez-Moreno, Andres   +1 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Digital Project-Based Learning in English Language Education: Instrument for Achieving Sustainable Development Goals

Jurnal Iqra': Kajian Ilmu Pendidikan
Digital Project-Based Learning (DPBL) represents an innovative pedagogical approach that integrates digital technologies within project-based learning to enhance English language education in alignment with the Sustainable Development Goals (SDGs ...
Angel Sophia Intan, Nidya Fitri, Yulia Wiji Astika, Teta Wismar   +3 more
doaj   +1 more source

An Approach for Management of Regional Portal Sites through Project-Based Learning [PDF]

, 2011
In this paper, we present an approach for management of regional portal sites through project-based learning. In this approach, we have developed a framework to regularly provide information systems and contents based on needs of regional communities for
Hiroshi, KOMATSUGAWA, Yasuhiro, HAYASHI, Yasushi, KIYOKI   +2 more
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

The Enhancement of Students’ Speaking Skills through Project-Based Learning in Non-Formal Education

Journal of English Education and Teaching
This study examines how Project-Based Learning (PBL) improves speaking skills in Paket C students at PKBM Kota Bekasi, an Indonesian non-formal education institution. This research aims to design and deploy customised PBL materials for these children and
Dini Hidayati, Leroy Holman Siahaan, Novi Andriani, Firtsa Malyda Putri   +3 more
doaj   +1 more source

MERANCANG KEGIATAN PEMBELAJARAN SEJARAH MELALUI KOMIK: RESPON TERHADAP TANTANGAN KURIKULUM 2013

Diakronika, 2017
Crucial issues, as well as the classic issues that have always been the subject of historical learning problems related to activities or learning processes that tend to be monotonous, boring and lack of innovation and creativity of the teachers in ...
Aisiah Anwar
doaj   +1 more source