Results 51 to 60 of about 13,433 (193)

PARTISIPASI MAHASISWA GEOGRAFI TERHADAP PELESTARIAN LINGKUNGAN MELALUI MODEL PEMBELAJARAN PROJECT BASED LEARNING DALAM KAJIAN KOTA HIJAU (GREEN CITIES)

open access: yesJurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2017
Human activities such as the conversion of agricultural land to unsustainable development, forest burning, environmental pollution and environmental indifference are factors of environmental damage.
Noviani Nurkolis   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

DEVELOPING PROFESSIONAL INFORMATION AND COMMUNICATION SKILLS THROUGH E-PROJECTS

open access: yesОбразование и наука, 2015
. The objective of the study is to show advantages of the method of e-projects. According to the authors of the publication, e-project based approach is a promising form of blended learning in universities. Methods.
Yulia V. Krasavina, M. Aiman Al Akkad
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Digital Project-Based Learning in English Language Education: Instrument for Achieving Sustainable Development Goals

open access: yesJurnal Iqra': Kajian Ilmu Pendidikan
Digital Project-Based Learning (DPBL) represents an innovative pedagogical approach that integrates digital technologies within project-based learning to enhance English language education in alignment with the Sustainable Development Goals (SDGs ...
Angel Sophia Intan   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

PENERAPAN PROJECT BASED LEARNING BERBASIS LINGKUNGAN UNTUK MENINGKATKAN KEAKTIFAN SISWA

open access: yesEdusaintek
Tujuan penelitian ini untuk meningkatkan aktivitas Pembelajaran Matematika dengan menerapkan Project Based Learning berbasis lingkungan kelas X SMK Muhammadiyah 2 Semarang.
Novi Ainun Marma Ubaidah   +2 more
doaj   +1 more source

MERANCANG KEGIATAN PEMBELAJARAN SEJARAH MELALUI KOMIK: RESPON TERHADAP TANTANGAN KURIKULUM 2013

open access: yesDiakronika, 2017
Crucial issues, as well as the classic issues that have always been the subject of historical learning problems related to activities or learning processes that tend to be monotonous, boring and lack of innovation and creativity of the teachers in ...
Aisiah Anwar
doaj   +1 more source

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