Results 71 to 80 of about 9,050 (220)

The TOP‐GERD Trial: Comparative Efficacy of Tegoprazan Versus Pantoprazole in the Treatment of Erosive Oesophagitis in a Non‐Asian Population

Alimentary Pharmacology &Therapeutics, EarlyView.
In this randomized, double‐blind trial in Mexican adults with erosive oesophagitis, tegoprazan did not significantly improve the primary 4‐week ITT healing endpoint versus pantoprazole (88.9% vs. 79.4%; p = 0.33), but produced faster symptom improvement. Encouraging per‐protocol and severe‐oesophagitis findings warrant confirmation.
José M. Remes‐Troche, Luis Raúl Valdovinos‐García, C. Prakash Gyawali, José Luis Vargas‐Basurto, Carlos Alberto Reyes‐Medina, Gisselle Vanessa González‐Hernández, A. Rafael Bernal Mendez, H. H. Barragán Cordova, Pablo Thomas‐Dupont, Peter Grube‐Pagola   +9 more
wiley   +1 more source

Modern options of prokinetics in gastroesophageal reflux disease treatment

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of the lecture. To present modern approaches to prokinetic treatment at gastroesophageal reflux disease (GERD) to gastroenterologists. Summary. GERD belongs to acid-related diseases, because detrimental action of hydrochloric acid on esophageal ...
A. A. Sheptulin, A. A. Kurbatova, S. A. Baranov   +2 more
doaj   +1 more source

Low-dose erythromycin in pediatrics: Formulation and stability of 20 mg hard gelatin capsules.

PLoS ONE, 2023
ObjectiveErythromycin is a macrolide antibiotic that is also prescribed off-label in premature neonates as a prokinetic agent. There is no oral formulation with dosage and/or excipients adapted for these high-risk patients.MethodsClinical studies of ...
Patrick Thevin, Christophe Curti, Alexandre Benech, Christophe Jean, Edouard Lamy, Caroline Castera Ducros, Nicolas Primas, Pierre Bertault-Peres, Patrice Vanelle   +8 more
doaj   +1 more source

CHARGE Syndrome: A Narrative Review and Update on Diagnosis, Assessment and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background CHARGE syndrome (CS) is a rare multisystemic genetic condition caused by a pathogenic variant in the DNA‐binding protein‐7 CHD7 gene. The condition affects the development of neural crest cells, which give rise to craniofacial structures, cranial nerves, ears, eyes and the heart, resulting in diverse and complex clinical features ...
Eleni M. van Gelder, Suzanna E. L. Temple, Niall Jefferson, David Brown, Kasee Stratton‐Gadke, Madelene Rich, Steve Rose, Kim Blake   +7 more
wiley   +1 more source

Role of ion channel modifiers in reversal of morphine-induced gastrointestinal inertia by prokinetic agents in mice

, 2008
Prokinetic drugs like mosapride, domperidone etc, are used to treat gastrointestinal delay. Though the receptor-mediated actions of these agents have been studied, involvement of ion channels in reversing morphine-induced gastrointestinal inertia by ...
Ramaswamy, Subramanian L. (7201359342), Dkhar, Steven Aibor (8088949300), Selvarajan, Sandhiya (55668491700), Krishna, Peddy Reddy Murali (34977071700)   +3 more
core   +1 more source

Systemic prokinetic pharmacologic treatment for postoperative adynamic ileus following abdominal surgery in adults

, 2008
BACKGROUND: Postoperative adynamic bowel atony interferes with recovery following abdominal surgery. Prokinetic pharmacologic drugs are widely used to accelerate postoperative recovery.
Pauli-Magnus, C, Bucher, H C, Brügger, L, Kunz, R, Traut, U, Haug, K, Ulrike Traut, Pauli-Magnus, C., Heiner Bucher, Bucher, H. C., Koller, M. T., Koller, M T, Kunz, R., Regina Kunz, Brügger, L., Traut, U., Haug, K., Lukas Brügger, Klaus Haug, Christiane Pauli-Magnus, Michael T. Koller, Kunz, Regina, Haug, Klaus, Traut, Ulrike, Bucher, Heiner, Brügger, Lukas, Koller, Michael T., Pauli-Magnus, Christiane   +27 more
core   +1 more source

Dose-dependent effects of mosapride citrate on duodenal and cecal motility in donkeys (Equus asinus)

International Journal of Veterinary Science and Medicine, 2013
Prokinetic drugs are used for the management of gastrointestinal motility disorders in horses; however, little is known about their efficacy in donkeys.
Naglaa A. Gomaa, Hussam M.M. Ibrahim, Mitsuo Ishii, Medhat N. Nassif, Sabry A. El-khodery   +4 more
doaj   +1 more source

Species and tissue-specificity of prokinetic, laxative and spasmodic effects of Fumaria parviflora [PDF]

, 2012
Background Fumaria parviflora Linn. (Fumariaceae), is a small branched annual herb found in many parts of the world including Saudi Arabia and Pakistan. This study was designed to provide pharmacological basis for the medicinal use of Fumaria parviflora ...
Al-Rehaily, Adnan J., Ramzi AA Mothana, Adnan J Al-Rehaily, Mothana, Ramzi A. A., Najeeb-ur-Rehman,, Anwar H Gilani, Mehmood, Malik Hassan, Malik Hassan Mehmood, Gilani, Anwar H., null Najeeb-ur-Rehman   +9 more
core   +2 more sources

Electroacupuncture Alleviates Comorbid Depression‐Like Behaviors and Dyspepsia‐Like Symptoms in Rats Accompanied by Alterations in Hippocampal Neuroinflammation and Gut Microbiota

Brain and Behavior, Volume 16, Issue 10, October 2026.
EA improves depression and dyspepsia via brain‐gut axis regulation ABSTRACT Background Depression and dyspepsia are highly comorbid in clinical practice, and their occurrence and progression are closely associated with dysfunction of the brain–gut axis.
Tianlang Wang, Yifan Feng, Xihan Wang, Yanan Xue, Jianbo Wang, Yi Qu, Tieming Ma, Jidong Liu   +7 more
wiley   +1 more source

Recurrent Congenital Hiatal Hernia After Laparoscopic Repair Complicated by Gastric Perforation and Abdominal Compartment Syndrome

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Complete excision of the hernial sac during congenital hiatal hernia repair may help prevent recurrence. This case also emphasizes the importance of early recognition and prompt management of abdominal compartment syndrome when progressive abdominal distension and organ dysfunction develop postoperatively.
Takayuki Fujii, Yui Noguchi, Nanami Harada, Hiroto Katami, Aya Tanaka   +4 more
wiley   +1 more source