Results 81 to 90 of about 9,050 (220)

Use of erythromycin and metoclopramide in hospitalized dogs: a multicenter historical cohort study

Frontiers in Veterinary Science
IntroductionProkinetics are used to treat gastrointestinal (GI) dysmotility in critically ill dogs but there have been no published studies characterizing their use. The objective of this multi-institutional retrospective cohort study was to describe the
Ee Fung Teo, Claire R. Sharp, Claire R. Sharp, Corrin J. Boyd, Weiqin Chee   +4 more
doaj   +1 more source

Effects of Tegaserod on Ileal Peristalsis of Guinea Pig In Vitro

Journal of Pharmacological Sciences, 2004
The mechanisms of prokinetic action of tegaserod in the gastrointestinal tract has not been studied in detail. The aim of this study was to investigate the effect of tegaserod on peristaltic reflexes and propagating peristaltic waves in guinea pig ileum.
Sang Won Ji, Hyojin Park, Jun Pyo Chung, Sang In Lee, Young Ho Lee   +4 more
doaj   +1 more source

Pediococcus acidilactici PA53 Supplementation Improves Stool Form and Modulates Gut Microbiota and Inflammatory Responses in Adults With Functional Constipation: A Randomized, Double‐Blind, Placebo‐Controlled Trial

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
In this randomized, double‐blind, placebo‐controlled trial, 8‐week supplementation with Pediococcus acidilactici PA53 significantly improved stool form in adults with functional constipation. PA53 supplementation was associated with changes in inflammatory markers and gut microbiota, including increased Pediococcus abundance.
Yuhan Xia, Yongmei Cai, Yongwei Zhang, Rui Cai, Hanshu Liu, Zhiwen Qiang   +5 more
wiley   +1 more source

A Multicenter, Prospective Real‐World Study of Simethicone–Activated Charcoal in Patients With Persistent Dyspeptic Symptoms Despite Acid Suppression (SIMAC Study)

JGH Open, Volume 10, Issue 10, October 2026.
ABSTRACT Background Persistent gas‐predominant dyspeptic symptoms affect many patients despite adequate proton pump inhibitor (PPI) therapy, reflecting mechanisms beyond acid secretion. We evaluated the real‐world effectiveness and safety of simethicone (80 mg) plus activated charcoal (250 mg) in adults with persistent symptoms despite prior PPI ...
Ashish Kumar, D. V. Sreenivas, Sambit Kumar Behera, Guduru Raghavendra Srinivas Rao, G. S. Sameer Kumar, Jaya Ghosh Chatterjee, Nalini Kant Choudhary, Ravi Shankar Bagepally, Shekhar Puri, S. M. A. Rizvi, Rahul Pathak, Shruti Pal   +11 more
wiley   +1 more source

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Decoding Finely Tuned Gamma Oscillations in Chronic Deep Brain Stimulation for Parkinson's Disease

Movement Disorders, Volume 41, Issue 10, Page 2677-2687, October 2026.
Abstract Background Finely tuned Gamma (FTG) activity—spontaneous narrowband Gamma oscillations (sFTG) or entrained to half the stimulation frequency (eFTG)—is typically linked to on‐medication states and dyskinesia in Parkinson's disease (PD), making it a potential physiomarker for adaptive deep brain stimulation (aDBS).
Marjolein Muller, Eline Anna Maria Yolanda Rouleau, Saskia van der Gaag, Rodi Zutt, Carel Frederik Ernst Hoffmann, Niels Anthony van der Gaag, Thomas Arjan van Essen, Alfred Christiaan Schouten, Maria Fiorella Contarino   +8 more
wiley   +1 more source

RANITIDINE POTENTIATES THE EFFECT OF METOCLOPRAMIDE ON GASTROINTESTINAL MOTILITY IN RABBITS

Pakistan Armed Forces Medical Journal, 2016
Objective: To explore the synergistic potential of ranitidine on prokinetic activity of metoclopramide on isolated duodenal model of rabbit. Study Design: Laboratory based randomized controlled trial.
Aroosa Ishtiaq Butt, Bushra Tayyaba Khan, Salman Bakhtiar   +2 more
doaj   +2 more sources

Risk of Clostridium difficile diarrhoea in critically ill patients treated with erythromycin-based prokinetic therapy for feed intolerance

, 2008
The original publication can be found at www.springerlink.comObjective To determine the incidence of Clostridium difficile (CD) diarrhoea in feed-intolerant, critically ill patients who received erythromycin-based prokinetic therapy.
Holloway, R., Ching, K., Nguyen, Q., Chapman, M., Fraser, R.   +4 more
core   +1 more source

Prokinetic and laxative effects of the crude methanolic extract of Viola betonicifolia whole plant in rodents [PDF]

, 2013
Background: The present study was aimed to provide ethnopharmacological basis for the medicinal use of Viola betonicifolia whole plant in indigestion and constipation.
Anwarul-Hassan Gilani, Saeed, Muhammad, Haroon Khan, Muhammad Saeed, Muhammad, Naveed, Khan, Haroon, Rehman,, Najeeb, Najeeb ur Rehman, Gilani, Anwar, Naveed Muhammad   +9 more
core   +2 more sources

Effect of GLP‐1 receptor agonist on nutrient intake: A narrative review

Nutrition in Clinical Practice, Volume 41, Issue 5, Page 1308-1317, October 2026.
Abstract Humans have a primitive defense mechanism called metabolic adaptation that slows voluntary weight loss. It works by downregulating hormones that reduce food intake and by lowering the metabolic rate. Second‐generation GLP‐1 receptor agonists, such as semaglutide or tirzepatide, promote weight loss by targeting this hormonal system to control ...
Ken Fujioka
wiley   +1 more source