Results 81 to 90 of about 435 (140)
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Gastroenterology Clinics of North America, 2015
Prokinetic agents are medications that enhance coordinated gastrointestinal motility and transit of content in the gastrointestinal tract, mainly by amplifying and coordinating the gastrointestinal muscular contractions. In addition to dietary therapy, prokinetic therapy should be considered as a means to improve gastric emptying and symptoms of ...
Andres, Acosta, Michael, Camilleri
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Prokinetic agents are medications that enhance coordinated gastrointestinal motility and transit of content in the gastrointestinal tract, mainly by amplifying and coordinating the gastrointestinal muscular contractions. In addition to dietary therapy, prokinetic therapy should be considered as a means to improve gastric emptying and symptoms of ...
Andres, Acosta, Michael, Camilleri
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The potential of ghrelin as a prokinetic
Regulatory Peptides, 2009Ghrelin is a 28 amino-acid peptide discovered in 1999. It is synthesized mainly in endocrine cells of the gastric mucosa and secreted into the blood. Physiological contributions of the peptide in human include probably regulation of growth hormone and of appetite.
Poitras, Pierre, Tomasetto, Catherine
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Prokinetics in Diabetic Gastroparesis
Current Gastroenterology Reports, 2012Within the last 50 years, diabetic gastroparesis has become a well recognized complication of type 1 and type 2 diabetes. It is a syndrome characterized by abnormal gastric function, resulting in delayed emptying of the stomach in the absence of any evident mechanical obstruction, predominantly manifested by early satiety, postprandial fullness, nausea,
Reza A, Hejazi +2 more
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Effects of Prokinetics on the Digestive Tract
Current Reviews in Clinical and Experimental Pharmacology, 2022Background: Functional gastrointestinal disorders account for at least a third of visits to gastroenterology clinics. Despite pathophysiological complexity, impaired gut motility may be frequently present in these disorders. Introduction: Prokinetics are a class of drugs that promote gastrointestinal motility, accelerate transit, and potentially ...
Paolo Usai-Satta +3 more
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Diabetic gastropathy and prokinetics
The American Journal of Gastroenterology, 2003The treatment of diabetic gastropathy, which here refers to a clinical syndrome of upper GI tract symptoms suggestive of an upper motility disturbance in diabetes whether or not there is delayed gastric emptying, remains suboptimal. New prokinetics and other motility-modifying agents may prove useful, but adequate clinical trials will be required to ...
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Clinical application of prokinetics
Veterinary Clinics of North America: Equine Practice, 2003Intestinal stasis or ileus is a significant cause of mortality and morbidity in horses and has been attributed to a variety of causes, including loss of intrinsic or extrinsic electrical activity, incoordination of contractile activity from regional stimuli, and dissociation between electrical and mechanical activity.
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Use of prokinetics in the preterm infant
Current Opinion in Pediatrics, 2011Functional gastrointestinal dysmotility is a common condition that affects premature infants. Delay in achievement of full enteral nutrition results in dependence on prolonged parenteral nutrition, predisposing to adverse outcomes. Studies in recent years show apparently conflicting results regarding the use of prokinetic agents in preterm infants ...
Hugh S, Lam, Pak C, Ng
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Prokinetic agents in the surgical patient
The American Journal of Surgery, 1999Surgeons may be confronted by several conditions that benefit from therapy with prokinetic agents. Prokinetic agents enhance contractile force, coordinate contractile activity, and accelerate transit in the gastrointestinal tract. Although some of these drugs may also have antiemetic effects, these are not the focus of this review.
J S, Thompson, E M, Quigley
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Prokinetics Influence the Pharmacokinetics of Rabeprazole
Digestion, 2008<i>Background:</i> Proton pump inhibitors (PPIs) are unstable at a low PH. Accelerated transfer of PPIs to the upper small intestine may influence the pharmacokinetics of PPIs. <i>Aim:</i> To see if concomitant use of mosapride citrate with rabeprazole sodium influences the pharmacokinetics of the PPI. <i>Methods:</i>
Katsuhito, Arai +5 more
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Cisapride: A Gastrointestinal Prokinetic Drug
Annals of Pharmacotherapy, 1994OBJECTIVE: To summarize the pharmacology, pharmacokinetics, efficacy, and safety of cisapride, and to evaluate its potential therapeutic role. DATA SOURCES: A computerized search of the MEDLINE database was used to identify English ...
J A, Barone +3 more
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