Results 101 to 110 of about 21,177 (122)
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Effect of Dietary Proline on Proline Metabolism in the Neonatal Pig
The Journal of Nutrition, 1989The effect of two dietary concentrations of proline (10.3 and 15.8 g/kg) on proline-metabolizing enzymes [pyrroline-5-carboxylate (P5C) reductase and proline oxidase], plasma and tissue free proline concentrations and growth were investigated in the 2- to 13-d-old pig. Diet had no effect on growth or enzyme activity. Diet had a significant (P less than
Henk L. M. Aarts +3 more
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Amino Acids, 2021
Cancer cells often change their metabolism to support uncontrolled proliferation. Proline is the only proteogenic secondary amino acid that is abundant in the body. Recent studies have shown that proline metabolism plays an important role in metabolic reprogramming and affects the occurrence and development of cancer.
Pengyu Geng, Wangshu Qin, Guowang Xu
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Cancer cells often change their metabolism to support uncontrolled proliferation. Proline is the only proteogenic secondary amino acid that is abundant in the body. Recent studies have shown that proline metabolism plays an important role in metabolic reprogramming and affects the occurrence and development of cancer.
Pengyu Geng, Wangshu Qin, Guowang Xu
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Plasma proline kinetics and the regulation of proline synthesis in man
Metabolism, 1987A quantitative exploration of the regulation of plasma proline concentration, proline oxidation, and proline endogenous biosynthesis was undertaken utilizing a 360-minute primed continuous infusion of L-[1-13C]proline and L-[methyl-2H3]leucine in healthy, postabsorptive young men.
Vernon R. Young +3 more
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Proline and Hydroxyproline in Leaves
Nature, 1952IN the course of investigations on the nitrogen metabolism of plants, the distribution of free amino-acids in the leaves of a number of plant species was studied by the circular paper chromatographic technique1. The occurrence of proline and hydroxy-proline in relatively high concentrations in some of the leaves investigated prompted us to report these
C. S. Vaidyanathan +3 more
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Proline metabolism in Escherichia coli
Analytical Biochemistry, 1966Abstract The location and quantitation of tritium in proline were achieved by successive oxidation of proline to γ-aminobutyric acid and thence to β-cyanopropionic acid. Although tritium kinetic isotope effects, whose magnitudes were estimated, attend the oxidations, the method can give unbiased results. Syntheses of proline-2- 3 H and proline-5- 3 H
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Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1997
Proline is unique among the 20 amino acids due to its cyclic structure. This specific conformation imposes many restrictions on the structural aspects of peptides and proteins and confers particular biological properties upon a wide range of physiologically important biomolecules.
Brendan O'Connor, Damian F. Cunningham
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Proline is unique among the 20 amino acids due to its cyclic structure. This specific conformation imposes many restrictions on the structural aspects of peptides and proteins and confers particular biological properties upon a wide range of physiologically important biomolecules.
Brendan O'Connor, Damian F. Cunningham
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Chemical Reviews
Within the canonical repertoire of the amino acid involved in protein biogenesis, proline plays a unique role as an amino acid presenting a modified backbone rather than a side-chain. Chemical structures that mimic proline but introduce changes into its specific molecular features are defined as proline analogues.
Vladimir Kubyshkin, Marina Rubini
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Within the canonical repertoire of the amino acid involved in protein biogenesis, proline plays a unique role as an amino acid presenting a modified backbone rather than a side-chain. Chemical structures that mimic proline but introduce changes into its specific molecular features are defined as proline analogues.
Vladimir Kubyshkin, Marina Rubini
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Proline and hepatic lipogenesis
Biochimica et Biophysica Acta (BBA) - General Subjects, 1984The effects of proline on lipogenesis in isolated rat hepatocytes were determined and compared with those of lactate, an established lipogenic precursor. Proline or lactate plus pyruvate increased lipogenesis (measured with 3H2O) in hepatocytes from fed rats depleted of glycogen in vitro and in hepatocytes from starved rats.
David I. Watts +3 more
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Chemistry – A European Journal, 2003
AbstractAccurate geometries, relative energies, rotational and quartic centrifugal distortion constants, dipole moments, harmonic vibrational frequencies, and infrared intensities were determined from ab initio electronic structure calculations for eighteen conformers of the neutral form of the amino acidL‐proline.
Eszter Czinki, Attila G. Császár
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AbstractAccurate geometries, relative energies, rotational and quartic centrifugal distortion constants, dipole moments, harmonic vibrational frequencies, and infrared intensities were determined from ab initio electronic structure calculations for eighteen conformers of the neutral form of the amino acidL‐proline.
Eszter Czinki, Attila G. Császár
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Metabolism of Proline and the Hydroxyprolines
Annual Review of Biochemistry, 1980PERSPECTIVES AND SUMMARY 1006 INTRODUCTION 1007 PROLINE 1008 Proline Biosynthesis: The Glutamate Pathway 1008 Proline Biosynthesis: The Om Pathway 1015 Proline Degradation: The P5C Pathway 1018 Proline Degradation: Reguiation 1020 Proline Degradation: Other Pathways 1023 4-HYDROXYPROLlNE 1024 Natural Occurrence 1024 Metabolism ...
Elijah Adams, Leonard Frank
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