Results 31 to 40 of about 21,177 (122)

N-acetyl proline-glycine-proline: implications for neurological disorders

Neural Regeneration Research, 2016
N-acetyl proline-glycine-proline (ac-PGP) is a matrix-derived chemoattractant, or matrikine, produced by the degradation of collagen. Ac-PGP was first identified in studies of alkali eye injury in rabbits (Pfister et al., 1995). The molecule was found to be a potent neutrophil chemoattractant and application of ac-PGP to the eye results in intense ...
Jeff W. Hill, Edwin M. Nemoto
openaire   +4 more sources

Efficacy of Put and Spd sprayed on leaves from Brassica juncea plants against Cd2+-induced oxidative stress [PDF]

arXiv, 2008
The protective effect exerted by polyamines (Put and Spd) against cadmium (Cd) stress was investigated in Brassica juncea plants. Treatment with CdCl2 (75 micro-Mole) resulted in a rise of Cd accumulation, a decrease of fresh and dry weights in every plant organ, an increase of free polyamine content at limb and stem levels as well as a decrease at ...
arxiv  

Label-free SERS Discrimination of Proline from Hydroxylated Proline at Single-molecule Level Assisted by a Deep Learning Model [PDF]

arXiv
Discriminating the low-abundance hydroxylated proline from hydroxylated proline is crucial for monitoring diseases and eval-uating therapeutic outcomes that require single-molecule sensors. While the plasmonic nanopore sensor can detect the hydrox-ylation with single-molecule sensitivity by surface enhanced Raman spectroscopy (SERS), it suffers from ...
arxiv  

Remarks on homo- and hetero-polymeric aspects of protein folding [PDF]

arXiv, 2003
Different aspects of protein folding are illustrated by simplified polymer models. Stressing the diversity of side chains (residues) leads one to view folding as the freezing transition of an heteropolymer. Technically, the most common approach to diversity is randomness, which is usually implemented in two body interactions (charges, polar character,..
arxiv  

Microscopic Mechanism of Specific Peptide Adhesion to Semiconductor Substrates [PDF]

Angew. Chem. Int. Ed. 49, 9530-9533 (2010); German Edition: Angew. Chem. 122, 9721-9724 (2010), 2011
The design of hybrid peptide-solid interfaces for nanotechnological applications such as biomolecular nanoarrays requires a deep understanding of the basic mechanisms of peptide binding and assembly at solid substrates. Here we show by means of experimental and computational analyses that the adsorption properties of mutated synthetic peptides at ...
arxiv  

Amino Acid Distributions and the Effect of Optimal Growth Temperature [PDF]

arXiv, 2013
We perform an exhaustive analysis of genome statistics for organisms, particularly extremophiles, growing in a wide range of physicochemical conditions. Specifically, we demonstrate how the correlation between the frequency of amino acids and their molecular weight, preserved on average, typically decreases as optimal growth temperature increases.
arxiv  

Zur Kenntnis der Oxy‐proline und über die Synthese von Oxy‐hygrinsäuren [PDF]

, 1908
Hermann Leuchs, Heinrich Felser
openalex   +1 more source

A Visual Interaction Framework for Dimensionality Reduction Based Data Exploration [PDF]

arXiv, 2018
Dimensionality reduction is a common method for analyzing and visualizing high-dimensional data. However, reasoning dynamically about the results of a dimensionality reduction is difficult. Dimensionality-reduction algorithms use complex optimizations to reduce the number of dimensions of a dataset, but these new dimensions often lack a clear relation ...
arxiv  

Liquid-liquid phase separation of proteins is modulated by amino acids in vitro and in vivo by regulating protein-protein interactions [PDF]

arXiv
Liquid liquid phase separation (LLPS) of proteins is an intracellular process that is widely used by cells for many purposes. In living cells (in vivo), LLPS occurs in complex and crowded environments. Amino acids (AAs) are vital components of such environments, occupying a significant fraction of the cellular volume.
arxiv  

Free energy, friction, and mass profiles from short molecular dynamics trajectories [PDF]

arXiv, 2018
We address the problem of constructing accurate mathematical models of the dynamics of molecular systems projected on a collective variable. To this aim we introduce an algorithm optimizing the parameters of a standard or generalized Langevin equation until the latter reproduces in a faithful way a set of molecular dynamics trajectories. In particular,
arxiv