Sources of superoxide/H2O2 during mitochondrial proline oxidation
Redox Biology, 2014 p53 Inducible gene 6 (PIG6) encodes mitochondrial proline dehydrogenase (PRODH) and is up-regulated several fold upon p53 activation. Proline dehydrogenase is proposed to generate radicals that contribute to cancer cell apoptosis.
Renata L.S. Goncalves +5 more
doaj +1 more source
Revista Brasileira de Engenharia Agrícola e Ambiental, 2023 The management adopted for the mango crop requires that, at a certain stage, the irrigation depth should be reduced to promote a more uniform flowering. In regard to that, it is necessary to introduce new alternatives that mitigate the harmful effects of
Luciana G. Sanches +6 more
doaj +1 more source
Uncovering the Mechanism of Aggregation of Human Transthyretin. [PDF]
, 2015 The tetrameric thyroxine transport protein transthyretin (TTR) forms amyloid fibrils upon dissociation and monomer unfolding. The aggregation of transthyretin has been reported as the cause of the life-threatening transthyretin amyloidosis.
Cascio, Duilio +9 more
core +2 more sources
Proline-Induced Modifications in Morpho-Physiological, Biochemical and Yield Attributes of Pea (Pisum sativum L.) Cultivars under Salt Stress [PDF]
, 2022 Sadia Shahid +8 more
openalex +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Investigation of Some Vegetative and Physiological Characteristic of Hammada salicornica Under Sand Burial [PDF]
مدیریت بیابان, 2018 This study investigated the vegetative and physiological characteristics of Hammada salicornica Syn.: Haloxylon salicornicum under sand burial. Experiment conducted in completely randomised design with five replicates.
Asghar Mosleh Arany +3 more
doaj +1 more source
Chromatographic separation and identification of some peptides in partial hydroylsates of gelatin [PDF]
, 1953 Recently we have been engaged in a study of the chemical structure of collagen and gelatin with the object of determining the sequence of the amino acid residues in the polypeptide chains of these proteins.
Green, F. Charlotte +2 more
core
Molecular mechanisms of adaptation of the moderately halophilic bacterium Halobacillis halophilus to its environment [PDF]
, 2013 The capability of osmoadaptation is a prerequisite of organisms that live in an environment with changing salinities. Halobacillus halophilus is a moderately halophilic bacterium that grows between 0.4 and 3 M NaCl by accumulating both chloride and ...
Hänelt, Inga, Müller, Volker
core +2 more sources
Impact of Drought on Soluble Sugars and Free Proline Content in Selected Arabidopsis Mutants
Biology, 2020 Simple Summary Drought has severe effects on plants, negatively impacting economic, agricultural and environmental processes. Depending on the duration and the strength of water stress conditions, plants adjust a series of physiological, cellular, and ...
L. Gurrieri +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source