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Author Correction: Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells. [PDF]
Park JM +14 more
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Schizophrenia-Like Behaviors Arising from Dysregulated Proline Metabolism Are Associated with Altered Neuronal Morphology and Function in Mice with Hippocampal PRODH Deficiency. [PDF]
Yao Y +9 more
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The circUbqln1, regulated by XBP1s, interplays with 14-3-3ΞΆ to inhibit collagen synthesis and promote osteoarthritis by controlling PRODH activity and proline metabolism. [PDF]
Feng N +17 more
europepmc +1 more source
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Amino Acids, 2021
Cancer cells often change their metabolism to support uncontrolled proliferation. Proline is the only proteogenic secondary amino acid that is abundant in the body. Recent studies have shown that proline metabolism plays an important role in metabolic reprogramming and affects the occurrence and development of cancer.
Wangshu Qin, Guowang Xu, Xu Guowang
exaly +3 more sources
Cancer cells often change their metabolism to support uncontrolled proliferation. Proline is the only proteogenic secondary amino acid that is abundant in the body. Recent studies have shown that proline metabolism plays an important role in metabolic reprogramming and affects the occurrence and development of cancer.
Wangshu Qin, Guowang Xu, Xu Guowang
exaly +3 more sources
Metabolism of Proline and the Hydroxyprolines
Annual Review of Biochemistry, 1980PERSPECTIVES AND SUMMARY 1006 INTRODUCTION 1007 PROLINE 1008 Proline Biosynthesis: The Glutamate Pathway 1008 Proline Biosynthesis: The Om Pathway 1015 Proline Degradation: The P5C Pathway 1018 Proline Degradation: Reguiation 1020 Proline Degradation: Other Pathways 1023 4-HYDROXYPROLlNE 1024 Natural Occurrence 1024 Metabolism ...
E, Adams, L, Frank
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Proline metabolism in cartilage: The importance of proline biosynthesis
Metabolism, 1978Abstract Mammalian cells have the capacity to synthesize proline from ornithine or glutamic acid, although preformed proline usually is available from extracellular sources. We have measured the rate of proline formation from ornithine in the presence of physiologic concentrations of proline. In rat xiphoid cartilage organ cultures with ornithine and
R J, Smith, J M, Phang
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