Results 31 to 40 of about 104,935 (243)
Proline: a key player in plant abiotic stress tolerance
Biologia Plantarum, 2015 Dramatic accumulation of proline is a common physiological response in plants exposed to various abiotic stresses. Accumulation of proline could be due to de novo synthesis, decreased degradation, lower utilization, or hydrolysis of proteins.
G. Kaur, B. Asthir
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Proline modulates the Trypanosoma cruzi resistance to reactive oxygen species and drugs through a novel D, L-proline transporter. [PDF]
PLoS ONE, 2014 Trypanosoma cruzi, the etiological agent of Chagas' disease, has a metabolism largely based on the consumption of glucose and proline. This amino acid is essential for host cells infection and intracellular differentiation.
Melisa Sayé +4 more
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Longevity Regulation by Proline Oxidation in Yeast
Microorganisms, 2021 Proline is a pivotal and multifunctional amino acid that is used not only as a nitrogen source but also as a stress protectant and energy source. Therefore, proline metabolism is known to be important in maintaining cellular homeostasis.
Akira Nishimura +5 more
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Intestinal proline is a potential anti-allergy factor for allergy diagnosis and therapy
Frontiers in Nutrition, 2022 Allergy has become a public health problem worldwide, but effective diagnostic and therapeutic approaches are limited currently. Amino acids are essential macronutrients that potentially participated in the allergy process. This work aimed to investigate
Jinya Ma +10 more
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Proline-dependent regulation of collagen metabolism [PDF]
Cellular and Molecular Life Sciences, 2019 AbstractThis review is focused on recent data on the role of proline (Pro) in collagen biosynthesis and cellular metabolism. It seems obvious that one of the main substrates for collagen biosynthesis Pro is required to form collagen molecule. The question raised in this review is whether the Pro for collagen biosynthesis is synthesized “de novo”, comes
Karna, Ewa +3 more
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The Metabolism of Proline as Microenvironmental Stress Substrate [PDF]
The Journal of Nutrition, 2008 Proline, a unique proteogenic secondary amino acid, has its own metabolic system with special features. Recent findings defining the regulation of this system led us to propose that proline is a stress substrate in the microenvironment of inflammation and tumorigenesis.
James M, Phang +2 more
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Rice, 2020 Background Global warming threatens rice growth and reduces yields. Proline plays important roles in plant abiotic stress tolerance. Previous research demonstrated that engineering proline metabolism-related genes can enhance tolerance to freezing and ...
Mingxin Guo +5 more
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The proline regulatory axis and cancer
Frontiers in Oncology, 2012 Studies in metabolism and cancer have characterized changes in core pathways involving glucose and glutamine, emphasizing the provision of substrates for building cell mass.
James Ming Phang
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Proline metabolism regulates replicative lifespan in the yeast Saccharomyces cerevisiae
Microbial Cell, 2019 In many plants and microorganisms, intracellular proline has a protective role against various stresses, including heat-shock, oxidation and osmolarity. Environmental stresses induce cellular senescence in a variety of eukaryotes.
Yukio Mukai +7 more
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Proline transport and metabolism in Rickettsia prowazekii [PDF]
Journal of Bacteriology, 1984 Purified Rickettsia prowazekii cells were able to transport L-proline. The influx of this amino acid had a Kt of 14 microM and a Vmax of about 64 pmol/min per mg of protein. Proline could not be transported by heat-killed or metabolically poisoned rickettsiae or at 0 degrees C. The uptake of proline was linear for almost 2 h.
H H, Winkler, R M, Daugherty
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