The study of a new and specific proline cleaving peptidase from bovine serum [PDF]
, 2003 Prolyl oligopeptidase is a serine peptidase characterised by oligoendopeptidase activity. Definitive evidence for the discrete biological role of prolyl oligopeptidase remains unknown, though its role in the maturation and degradation of peptide hormones
Collins, Patrick
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Formulation, Characterisation and Evaluation of the Antihypertensive Peptides, Isoleucine-Proline-Proline and Leucine-Lysine-Proline in Chitosan Nanoparticles Coated with Zein for Oral Drug Delivery [PDF]
, 2023 Isoleucine-Proline-Proline (IPP) and Leucine-Lysine-Proline (LKP) are food-derived tripeptides whose antihypertensive functions have been demonstrated in hypertensive rat models.
Danish, Minna K. +4 more
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Heliyon, 2019 Background: In response to various environmental stresses, many plant species synthesize L-proline in the cytosol and accumulates in the chloroplasts. L-Proline accumulation in plants is a well-recognized physiological reaction to osmotic stress prompted
Mukesh Meena +7 more
doaj +1 more source
Journal of Integrative Agriculture, 2023 Mangoes often suffer from low temperature-induced chilling injury (CI) during postharvest cold storage. Therefore, advanced techniques are crucial and in high demand to solve the chilling stress of mango fruit for a higher value.
Mariama KEBBEH +4 more
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The effect of water deficit and excess copper on proline metabolism in Nicotiana benthamiana
, 2012 Fluctuation in proline content is a widespread phenomenon among plants in response to heavy metal stress. To distinguish between the participation of water deficit and copper on changes in proline metabolism, potted plants and floating leaf discs of ...
C. -W. Tan +5 more
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PRODH/POX-Dependent Celecoxib-Induced Apoptosis in MCF-7 Breast Cancer
Pharmaceuticals, 2021 Celecoxib (Cx), an inhibitor of cyclooxygenase 2, induces apoptosis of cancer cells. However, the mechanism of the chemopreventive effect remains not fully understood.
Magdalena Misiura +4 more
doaj +1 more source
Changes in morphology, proline content, and palatability to Helix aspersa, in Plantago lanceolata in response to transplantation and polluted soil [PDF]
, 1992 High concentrations of heavy metals are a cause of stress in plants, many of which respond by accumulating high levels of the amino acid proline. Tolerant and intolerant plants may vary in their response, and this may be reflected in the palatability of ...
Lart, K.M.
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Serine-404 Phosphorylation and the R406W Modification in Tau Stabilize the cis-Proline Amide Bond, via Phosphoserine-Proline C–H/O and Proline-Aromatic C–H/π Interactions [PDF]
, 2023 Tau misfolding, oligomerization, and aggregation are central to the pathology of Alzheimer\u27s disease (AD), chronic traumatic encephalopathy (CTE), frontotemporal dementia, and other tauopathies.
Michael B., Elbaum +2 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Effect of drought stress on yield, proline and chlorophyll contents in three chickpea cultivars [PDF]
, 2010 Drought stress is one of the major abiotic stresses in agriculture worldwide. This study was carried out to investigate the effect of drought stress on proline content, chlorophyll content, photosynthesis and transpiration, stomatal conductance and yield
Siosemardeh, A. +4 more
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