Results 71 to 80 of about 195,829 (321)
Comparative genome-centric analysis reveals seasonal variation in the function of coral reef microbiomes [PDF]
, 2020 Microbially mediated processes contribute to coral reef resilience yet, despite extensive characterisation of microbial community variation following environmental perturbation, the effect on microbiome function is poorly understood.
Bourne, David G. +6 more
core +2 more sources
Heliyon, 2019 Background: In response to various environmental stresses, many plant species synthesize L-proline in the cytosol and accumulates in the chloroplasts. L-Proline accumulation in plants is a well-recognized physiological reaction to osmotic stress prompted
Mukesh Meena +7 more
doaj +1 more source
Proline oxidase controls proline, glutamate, and glutamine cellular concentrations in a U87 glioblastoma cell line. [PDF]
PLoS ONE, 2018 L-Proline is a multifunctional amino acid that plays an essential role in primary metabolism and physiological functions. Proline is oxidized to glutamate in the mitochondria and the FAD-containing enzyme proline oxidase (PO) catalyzes the first step in ...
Pamela Cappelletti +5 more
doaj +1 more source
MTOR cross-talk in cancer and potential for combination therapy [PDF]
, 2018 The mammalian Target of Rapamycin (mTOR) pathway plays an essential role in sensing and integrating a variety of exogenous cues to regulate cellular growth and metabolism, in both physiological and pathological conditions.
Bazzichetto, C. +7 more
core +3 more sources
The Multifaceted Roles of Proline in Cell Behavior
Frontiers in Cell and Developmental Biology, 2021 Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino acid is: (i) A main precursor of extracellular collagens (the most abundant human proteins), antimicrobial peptides (involved in innate immunity), salivary ...
Eduardo J. Patriarca +6 more
doaj +1 more source
Proline transport and metabolism in Rickettsia prowazekii [PDF]
Journal of Bacteriology, 1984 Purified Rickettsia prowazekii cells were able to transport L-proline. The influx of this amino acid had a Kt of 14 microM and a Vmax of about 64 pmol/min per mg of protein. Proline could not be transported by heat-killed or metabolically poisoned rickettsiae or at 0 degrees C. The uptake of proline was linear for almost 2 h.
H H, Winkler, R M, Daugherty
openaire +2 more sources
Frontiers in Plant Science, 2019 Plants have to adapt their metabolism to constantly changing environmental conditions, among which the availability of light and water is crucial in determining growth and development.
Hajnalka Kovács +9 more
doaj +1 more source
PRODH/POX-Dependent Celecoxib-Induced Apoptosis in MCF-7 Breast Cancer
Pharmaceuticals, 2021 Celecoxib (Cx), an inhibitor of cyclooxygenase 2, induces apoptosis of cancer cells. However, the mechanism of the chemopreventive effect remains not fully understood.
Magdalena Misiura +4 more
doaj +1 more source
Effect of drought stress on yield, proline and chlorophyll contents in three chickpea cultivars [PDF]
, 2010 Drought stress is one of the major abiotic stresses in agriculture worldwide. This study was carried out to investigate the effect of drought stress on proline content, chlorophyll content, photosynthesis and transpiration, stomatal conductance and yield
Bahramnejad, B. +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source