Results 81 to 90 of about 1,032,868 (266)

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Melatonin Combined with 1-Methylcyclopropene Regulates Proline Metabolism to Alleviate Chilling Injury in Postharvest Hami Melons [PDF]

Shipin Kexue
To investigate the effects of melatonin (MT) in combination with 1-methylcyclopropene (1-MCP) on postharvest proline metabolism and chilling injury in Hami melons, this study included four treatments: control (distilled water immersion + distilled water ...
WANG Xiaobing, JIA Meihui, GAO Zhongchuan, CHEN Haixin, CHEN Xiaojie, ZHANG Zonghao, WENG Wanlin, WANG Yu, WANG Jing
doaj   +1 more source

Seedlings' growth in response to drought stress and 2,4-dichlorophenoxyacetic acid (2,4-D) [PDF]

, 1989
The aim of this work was to study the effect of the herbicide, 2,4-D on a mono- cot (Lolium temulentum Linn.) and a dicot (Raphanus sativus Linn.) in relation to drought stress, in order to elucidate if the combined treatments altered the survival of the
Alaib, M. A.
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Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Emerging Roles of De Novo Proline Biosynthesis in Human Diseases

FASEB BioAdvances
De novo proline synthesis is a highly conserved and essential biochemical pathway in mammals. Beyond serving as a fundamental building block for proteins, proline also plays key roles in diverse cellular functions and maintaining tissue homeostasis. Over
Ethan Pei, Junfeng Ma
doaj   +1 more source

Humic Acid Alleviates Low-Temperature Stress by Regulating Nitrogen Metabolism and Proline Synthesis in Melon (Cucumis melo L.) Seedlings

Horticulturae
Melon is a thermophilic crop that is extremely sensitive to temperature changes. Humic acid (HA) is an eco-friendly biostimulant that enhances plants against abiotic stresses.
Libao Zhu, Haihe Liu, Yanping Zhang, Yanxia Cao, Yiwen Hu, Yalun Wang, Haiqiang Zheng, Mengze Liu   +7 more
doaj   +1 more source

Proline dehydrogenase regulates redox state and respiratory metabolism in Trypanosoma cruzi. [PDF]

PLoS ONE, 2013
Over the past three decades, L-proline has become recognized as an important metabolite for trypanosomatids. It is involved in a number of key processes, including energy metabolism, resistance to oxidative and nutritional stress and osmoregulation.
Lisvane Silva Paes, Brian Suárez Mantilla, Flávia Menezes Zimbres, Elisabeth Mieko Furusho Pral, Patrícia Diogo de Melo, Erich B Tahara, Alicia J Kowaltowski, Maria Carolina Elias, Ariel Mariano Silber   +8 more
doaj   +1 more source

NaCl-Regulated gene expression in Distichlis [PDF]

, 1994
NaCl-induced and -repressed cDNA clones had previously been isolated by differential screening of a cDNA library, prepared from poly(A(^+)) RNA isolated from Distichlis spicata (salt grass) cell cultures grown in the presence of 260 mM NaCl (Zhao, et al.,
Furniss, Caroline S.M.
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Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

The accumulation of the stress metabolite praline in plantago lanceolata as a response to lead pollution [PDF]

, 1990
The amino acid proline is known to accumulate in the tissues of several plant species as a result of environmental stress. High concentrations of certain toxic metals are one form of stress that can induce proline accumulation, and in some cases praline ...
Hanley, M.E.
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