Results 21 to 30 of about 1,083,777 (264)

Proline and ROS: A Unified Mechanism in Plant Development and Stress Response? [PDF]

Plants
The proteinogenic amino acid proline plays crucial roles in both plant development and stress responses, far exceeding its role in protein synthesis. However, the molecular mechanisms and the relative importance of these additional functions of proline ...
Marco Renzetti, Dietmar Funck, Maurizio Trovato   +2 more
doaj   +2 more sources

Proline Metabolism in Tumor Growth and Metastatic Progression [PDF]

Frontiers in Oncology, 2020
Cancer cells show a formidable capacity to survive under stringent conditions, to elude mechanisms of control, such as apoptosis, and to resist therapy.
Cristina D'Aniello, Eduardo J. Patriarca, James M. Phang, Gabriella Minchiotti   +3 more
doaj   +4 more sources

Proline Metabolism in Malignant Gliomas: A Systematic Literature Review. [PDF]

Cancers (Basel), 2022
Aim of the study is to systematically review the published data concerning proline metabolism in malignant brain tumors of glial ...
Sawicka MM, Sawicki K, Łysoń T, Polityńska B, Miltyk W.   +4 more
europepmc   +3 more sources

Humic Acid Alleviates Low-Temperature Stress by Regulating Nitrogen Metabolism and Proline Synthesis in Melon (Cucumis melo L.) Seedlings

Horticulturae
Melon is a thermophilic crop that is extremely sensitive to temperature changes. Humic acid (HA) is an eco-friendly biostimulant that enhances plants against abiotic stresses.
Libao Zhu, Haihe Liu, Yanping Zhang, Yanxia Cao, Yiwen Hu, Yalun Wang, Haiqiang Zheng, Mengze Liu   +7 more
doaj   +2 more sources

Proline Metabolism in Neurological and Psychiatric Disorders. [PDF]

Mol Cells, 2022
Proline plays a multifaceted role in protein synthesis, redox balance, cell fate regulation, brain development, and other cellular and physiological processes. Here, we focus our review on proline metabolism in neurons, highlighting the role of dysregulated proline metabolism in neuronal dysfunction and consequently neurological and psychiatric ...
Yao Y, Han W.
europepmc   +3 more sources

Modified Proline Metabolism and Prolidase Enzyme in COVID-19. [PDF]

Lab Med, 2022
OBJECTIVE: The aim of the study was to evaluate proline metabolism in patients affected by COVID-19. MATERIALS AND METHODS: This case-control study consisted of 116 patients with COVID-19 and 46 healthy individuals.
Ergin Tuncay M, Neselioglu S, Asfuroglu Kalkan E, Inan O, Sena Akkus M, Ates I, Erel O.   +6 more
europepmc   +2 more sources

Proline metabolism regulation in Spartina alterniflora and SaP5CS2 gene positively regulates salt stress tolerance in transgenic Arabidopsis thaliana

Journal of Plant Interactions, 2022
It has been discovered that many plants accumulate proline in response to osmotic stress. However, the interaction between salinity stress and proline metabolism-related genes has not been unequivocally identified in Spartina alterniflora.
Yang Zhao, Yingying He, Xixi Wang, Changfeng Qu, Jinlai Miao   +4 more
doaj   +1 more source

Yeast homologs of human MCUR1 regulate mitochondrial proline metabolism [PDF]

, 2020
Mitochondria house evolutionarily conserved pathways of carbon and nitrogen metabolism that drive cellular energy production. Mitochondrial bioenergetics is regulated by calcium uptake through the mitochondrial calcium uniporter (MCU), a multi-protein ...
Trivedi, P., Madesh, M., Chen, Y., Watrous, J., Timbalia, S., Zulkifli, M., Nilsson, R., Anderson, S., Jain, M., Murgia, M., Gohil, V., Neff, J., Garza, N., Tomar, D.   +13 more
core   +3 more sources

Drought-induced proline is mainly synthesized in leaves and transported to roots in watermelon under water deficit

Horticultural Plant Journal, 2022
Proline accumulation has been shown to occur in plants in response to various environmental stresses. Although proline metabolism-related genes have been functionally characterized, the inter-organ transport of proline in stressed plants remains unclear.
Zhongyuan Wang, Yongchao Yang, Vivek Yadav, Wei Zhao, Yaping He, Xian Zhang, Chunhua Wei   +6 more
doaj   +1 more source

Mitochondrial dynamics links PINCH-1 signaling to proline metabolic reprogramming and tumor growth

Cell Stress, 2020
Proline metabolism is critical for cellular response to microenvironmental stress in living organisms across different kingdoms, ranging from bacteria, plants to animals. In bacteria and plants, proline is known to accrue in response to osmotic and other
Ling Guo, Chuanyue Wu
doaj   +1 more source