Results 21 to 30 of about 1,032,868 (266)
Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells [PDF]
Experimental and Molecular MedicineFerritin, comprising heavy (FTH1) and light (FTL) chains, is the main iron storage protein, and pancreatic cancer patients exhibit elevated serum ferritin levels.
Ji Min Park +14 more
doaj +2 more sources
Can proline dehydrogenase—a key enzyme involved in proline metabolism—be a novel target for cancer therapy? [PDF]
Frontiers in Oncology, 2023 Guang Ji, Weina Xu
exaly +2 more sources
Proline Metabolism in Neurological and Psychiatric Disorders. [PDF]
Mol Cells, 2022 Proline plays a multifaceted role in protein synthesis, redox balance, cell fate regulation, brain development, and other cellular and physiological processes. Here, we focus our review on proline metabolism in neurons, highlighting the role of dysregulated proline metabolism in neuronal dysfunction and consequently neurological and psychiatric ...
Yao Y, Han W.
europepmc +3 more sources
Modified Proline Metabolism and Prolidase Enzyme in COVID-19. [PDF]
Lab Med, 2022 OBJECTIVE: The aim of the study was to evaluate proline metabolism in patients affected by COVID-19. MATERIALS AND METHODS: This case-control study consisted of 116 patients with COVID-19 and 46 healthy individuals.
Ergin Tuncay M +6 more
europepmc +2 more sources
Proline Metabolism in Malignant Gliomas: A Systematic Literature Review. [PDF]
Cancers (Basel), 2022 Background: Proline has attracted growing interest because of its diverse influence on tumor metabolism and the discovery of the regulatory mechanisms that appear to be involved.
Sawicka MM +4 more
europepmc +2 more sources
Journal of Plant Interactions, 2022 It has been discovered that many plants accumulate proline in response to osmotic stress. However, the interaction between salinity stress and proline metabolism-related genes has not been unequivocally identified in Spartina alterniflora.
Yang Zhao +4 more
doaj +1 more source
Horticultural Plant Journal, 2022 Proline accumulation has been shown to occur in plants in response to various environmental stresses. Although proline metabolism-related genes have been functionally characterized, the inter-organ transport of proline in stressed plants remains unclear.
Zhongyuan Wang +6 more
doaj +1 more source
Mitochondrial dynamics links PINCH-1 signaling to proline metabolic reprogramming and tumor growth
Cell Stress, 2020 Proline metabolism is critical for cellular response to microenvironmental stress in living organisms across different kingdoms, ranging from bacteria, plants to animals. In bacteria and plants, proline is known to accrue in response to osmotic and other
Ling Guo, Chuanyue Wu
doaj +1 more source
NITROGEN METABOLISM OF SOYBEAN AT SATURATED SOIL CULTURE AND WATERING CULTIVATION OF FARMER’S SYSTEM IN CONDITIONS OF TIDAL LAND [PDF]
Russian Journal of Agricultural and Socio-Economic Sciences, 2023 This research aimed to study the effect of the water-saturated cultivation system of Tidal land on nitrogen metabolism in soybean. Treatment was growing plants on benches, at the different water levels of trenches-which were 15 cm, 20 cm, and 25 cm from ...
Mapegau M. +4 more
doaj +1 more source
Inborn Errors of Proline Metabolism [PDF]
The Journal of Nutrition, 2008 l-Proline concentration is primarily related to the balance of enzymatic activities of proline dehydrogenase [proline oxidase (POX)] and Delta-1-pyrroline-5-carboxylate (P5C) reductase. As a result, P5C plays a pivotal role in maintaining the concentration of proline in body fluids and inborn errors of P5C metabolism lead to disturbance of proline ...
Hiroshi, Mitsubuchi +3 more
openaire +2 more sources