Results 181 to 190 of about 263,845 (214)

Proline Reduces Brain Cytochrome c Oxidase: Prevention by Antioxidants

International Journal of Developmental Neuroscience, 2007
In the present study, we initially investigated the in vivo (acute and chronic) and in vitro effects of proline on cytochrome c oxidase (complex IV) activity in rat cerebral cortex to test the hypothesis that proline might alter energy metabolism and ...
Angela T.S. Wyse, Fábria Chiarani, Débora Delwing   +2 more
exaly   +2 more sources

Hydrogen Peroxide Produced by NADPH Oxidases Increases Proline Accumulation During Salt or Mannitol Stress in Arabidopsis thaliana

New Phytologist, 2015
International audienceMany plants accumulate proline, a compatible osmolyte, in response to various environmental stresses such as water deficit and salinity.
Arnould Savouré, Anne-Sophie Leprince, Chedly Abdelly   +2 more
exaly   +2 more sources

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PROLINE OXIDASES IN HANSENULA SUBPELLICULOSA

Journal of Bacteriology, 1964
Ling, Chung-Mei (Illinois Institute of Technology, Chicago), and L. R. Hedrick . Proline oxidases in Hansenula subpelliculosa . J. Bacteriol. 87: 1462–1470.
C M, LING, L R, HEDRICK
openaire   +2 more sources

Prolidase-Proline Dehydrogenase/Proline Oxidase-Collagen Biosynthesis Axis as a Potential Interface of Apoptosis/Autophagy

BioFactors, 2016
AbstractProlidase is a cytosolic imidodipeptidase that specifically splits imidodipeptides with C‐terminal proline or hydroxyproline. The enzyme plays an important role in the recycling of proline from imidodipeptides for resynthesis of collagen and other proline‐containing proteins.
Ilona Oscilowska, Jerzy Pałka
exaly   +3 more sources

Glucocorticoid control of hepatic proline oxidase

Metabolism, 1977
Since adrenal corticosteroids are known to affect amino acid metabolism and gluconeogenesis, we examined the relationship of these hormones to hepatic proline oxidase, the mitochondrial enzyme degrading L-proline. In adrenalectomized rats hepatic proline oxidase activity decreased to about 50% of control levels within 5-6 days.
E M, Kowaloff, A S, Granger, J M, Phang
openaire   +2 more sources

Proline oxidase in cultured mammalian cells

Journal of Cellular Physiology, 1977
AbstractWe sought a cultured cell line with Proline Oxidase activity to study the regulation and physiologic role of the enzyme in mammalian tissues. Among the cell lines tested, only LLC‐RK1 cells, derived from rabbit kidney, had significant Proline Oxidase activity; the Km for proline of the enzyme from these cells was similar to that for the liver ...
S J, Downing, J M, Phang, E M, Kowaloff, D, Valle, R J, Smith   +4 more
openaire   +2 more sources

Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis

Molecular and Cellular Biochemistry, 2006
Proline oxidase (POX), a mitochondrial inner-membrane protein, catalyzes the rate-limiting oxidation of proline to pyrroline- 5-carboxylate (P5C). Previously we showed that overexpression of POX is associated with generation of reactive oxygen species (ROS) and apoptosis in POX-inducible colorectal cancer cells, DLD-1.POX.
Chien-an A, Hu, Steven P, Donald, Jian, Yu, Wei-Wen, Lin, Zhihe, Liu, Gary, Steel, Cassandra, Obie, David, Valle, James M, Phang   +8 more
openaire   +2 more sources

Characteristics of proline oxidase in rat tissues.

Journal of biochemistry, 1980
In adult rats the activity of proline oxidase is high in the liver and kidney and moderate in the brain and heart, but it is not detectable in the lung, skeletal muscle, spleen, or small intestine. The activity in the liver is 1.5 times higher in females than males.
Y, Kawabata, N, Katunuma, Y, Sanada
openaire   +3 more sources

Glucocorticoid induction of proline oxidase in LLC‐RK1 cells

Journal of Cellular Physiology, 1978
AbstractDexamethasone induced proline oxidase in cultured LLC‐RK1 cells, an epithelial cell line derived from rabbit kidney. The dexamethasone‐mediated increase in enzyme activity was concentration and time dependent. Although the effect could be dissociated from cell growth and cell density, it was dependent on protein and RNA synthesis.
E M, Kowaloff, J M, Phang, A S, Granger, S J, Downing   +3 more
openaire   +2 more sources

Proline Oxidase Inhibition by Free Fatty Acids of Rat Pancreas

Biochimica Et Biophysica Acta - Biomembranes, 1980
Proline oxidase activity was not measurable in pancreas homogenate but was measurable in pancreas slices. Moreover, added pancreas homogenate inhibited proline oxidase activity in rat liver mitochondria and several other tissues. The partially purified inhibitor from pancreas also inhibited the activity of glutamate, glucose 6-phosphate, NADH and ...
W Eugene Knox, G M Patton, W E Knox
exaly   +3 more sources