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A proof-of-concept study: investigating the impact of COMT genotype and proline on negative symptoms in Alzheimer's disease. [PDF]

open access: yesBJPsych Open
Clelland JD   +10 more
europepmc   +1 more source
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Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis

Molecular and Cellular Biochemistry, 2006
Proline oxidase (POX), a mitochondrial inner-membrane protein, catalyzes the rate-limiting oxidation of proline to pyrroline- 5-carboxylate (P5C). Previously we showed that overexpression of POX is associated with generation of reactive oxygen species (ROS) and apoptosis in POX-inducible colorectal cancer cells, DLD-1.POX.
Chien-an A, Hu   +8 more
openaire   +4 more sources

Prolidase‐proline dehydrogenase/proline oxidase‐collagen biosynthesis axis as a potential interface of apoptosis/autophagy

BioFactors, 2016
AbstractProlidase is a cytosolic imidodipeptidase that specifically splits imidodipeptides with C‐terminal proline or hydroxyproline. The enzyme plays an important role in the recycling of proline from imidodipeptides for resynthesis of collagen and other proline‐containing proteins.
Ilona, Zareba, Jerzy, Palka
openaire   +4 more sources

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