Results 111 to 120 of about 18,044 (216)

Full Paper Novel Spiroannulated 3-Benzofuranones. Synthesis and

open access: yes, 2008
: The novel 3H-spiro[1-benzofuran-2-cyclopentan]-3-one skeleton has been made accessible by different routes. One- and two-step protocols lead to tricyclic and tetracyclic benzofuranones 2 and 3, respectively.
Anahita Hessamian-alinejad   +6 more
core  

Cotton Bollworm (H. armigera) Effector PPI5 Targets FKBP17‐2 to Inhibit ER Immunity and JA/SA Responses, Enhancing Insect Feeding

open access: yesAdvanced Science
The cotton bollworm causes severe mechanical damage to plants during feeding and leaves oral secretions (OSs) at the mechanical wounds. The role these OSs play in the invasion of plants is still largely unknown. Here, a novel H.
Yaxin Wang   +11 more
doaj   +1 more source

The prolyl isomerase Pin1 is overexpressed in human esophageal cancer

open access: yes, 2011
Peptidyl-prolyl isomerase Pint specifically catalyzes the cis/trans-isomerization of proline in the target sequence of phosphorylated Ser/Thr-Pro in over 50 critical regulatory proteins.
Sun, Lifang   +8 more
core   +1 more source

Drosophila peptidyl-prolyl cis/trans isomerase-like 4 regulates circadian rhythm by supporting high-amplitude oscillations of PERIOD

open access: yesiScience
Summary: Peptidyl-prolyl cis/trans isomerases (PPIases) accelerate proline peptide bond isomerization, affecting substrate protein function. In this study, through RNAi-based behavioral screening of PPIases in Drosophila melanogaster, we identified ...
So Who Kang   +5 more
doaj   +1 more source

Characterisation of the PrtM maturase of Streptococcus equi; a proven virulence factor in strangles

open access: yes
Streptococcus equi subspecies equi (S. equi) is the pathogen responsible for the prevalent and highly contagious equine disease called strangles. Strangles has been reported worldwide as a cause of a high level of animal suffering and economic loss.
Ikolo, Felicia
core  

The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex

open access: yesNature Communications
Collagen posttranslational processing is crucial for its proper assembly and function. Disruption of collagen processing leads to tissue development and structure disorders like osteogenesis imperfecta (OI).
Wenguo Li   +13 more
doaj   +1 more source

GPR97 variants and their influence on pathological myopia: implications for glucocorticoid treatment

open access: yesResearch in Pharmaceutical Sciences
Background and purpose: Pathologic myopia (PM) is a severe form of myopia associated with structural changes in the eye, leading to vision impairment. Identifying genetic factors that contribute to PM can enhance the treatment of the condition.
Qi Zhao   +7 more
doaj   +1 more source

The role of peptidyl-prolyl isomerase Pin1 in neuronal signaling in epilepsy. [PDF]

open access: yesFront Mol Neurosci, 2022
Chen Y   +8 more
europepmc   +1 more source

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