Results 121 to 130 of about 18,044 (216)

Novel Approaches for the Modulation of Pin1 Prolyl Isomerase Activity

open access: yes
Pin1 is a peptidyl-prolyl isomerase that catalyses the cis-trans isomerisation of proteins at phosphorylated serine-proline and threonine-proline motifs (pS/pT-P).
Adem Ozleyen (7533248)
core   +1 more source

Pin1 and Par14 Peptidyl Prolyl Isomerase Inhibitors Block Cell Proliferation

open access: yes, 2003
Disruption of the parvulin family peptidyl prolyl isomerase (PPIase) Pin1 gene delays reentry into the cell cycle when quiescent primary mouse embryo fibroblasts are stimulated with serum.
Takahashi, Morito   +10 more
core   +1 more source

Targeting peptidyl-prolyl isomerase 1 in experimental pulmonary arterial hypertension. [PDF]

open access: yesEur Respir J, 2022
Rai N   +12 more
europepmc   +1 more source

Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation

open access: yes, 2010
[[abstract]]The serine/threonine protein kinase B (PKB, also known as Akt) plays a pivotal role in diverse cellular functions. Elevated expression of activated Akt has been detected in a wide variety of human cancers; however, the mechanism of Akt ...
Liao, Y (Liao, Y.); Wei, Y (Wei, Y.); Zhou, X (Zhou, X.); Yang, JY (Yang, J-Y); Dai, C (Dai, C.); Chen, YJ (Chen, Y-J); Agarwal, NK (Agarwal, N. K.); Sarbassov, D (Sarbassov, D.); Shi, D (Shi, D.); Yu, D (Yu, D.); Hung, MC (Hung, M-C)
core   +1 more source

Prolyl Isomerase Pin1 Expression in the Spinal Motor Neurons of Patients With Sporadic Amyotrophic Lateral Sclerosis. [PDF]

open access: yesJ Clin Neurol, 2022
Kato H   +7 more
europepmc   +1 more source

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