Results 21 to 30 of about 12,746 (209)
Benzimidazole derivatives endowed with potent antileishmanial activity
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Two sets of benzimidazole derivatives were synthesised and tested in vitro for activity against promastigotes of Leishmania tropica and L. infantum. Most of the tested compounds resulted active against both Leishmania species, with IC50 values in the low
Michele Tonelli +8 more
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Microorganisms, 2023 Leishmaniasis is a protozoan disease responsible for significant morbidity and mortality. There is no recommended vaccine to protect against infection.
Derya Topuz Ata +5 more
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Metaciclogénesis: un proceso fundamental en la biología de Leishmania
Biomédica: revista del Instituto Nacional de Salud, 2002 La metaciclogénesis es un proceso que experimentan naturalmente los promastigotes de Leishmania en el tracto digestivo del insecto vector y cuya finalidad es transformar los promastigotes en formas altamente infectivas y capaces de sobrevivir en el ...
Carlos E. Muskus, Marcel Marín Villa
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Pathogens, 2023 We previously showed that L. (Leishmania) amazonensis promastigotes and amastigotes of the PH8 strain generated larger lesions in mice than LV79, and that lesion-derived amastigotes from the two strains differ in their proteomes.
Fabia Tomie Tano +7 more
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PURIFICATION OF METACYCLIC LEISHMANIAL PROMASTIGOTES BY USING PEANUT LECTIN AGGLUTININ TEST . [PDF]
Basrah Journal of Veterinary Research, 2017 Lieshmania metacyclic promastigotes are transmitted during blood meals after development inside the gut of the sandfly vector. The isolation from axenic cultures of procyclic and metacyclic promastigotes by peanut lectin agglutination followed by ...
NuhaS. Al-Bayati +2 more
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Antileishmanial activity of auranofin against Leishmania major in vitro
International Archives of Health Sciences, 2022 Aim: Despite the various studies done in the field of cutaneous leishmaniasis treatment, there is still no perfect and safe drug for definite treatment of this disease. Therefore, the quest to find an appropriate drug continues.
Mohammad Ezati Mehmandust Olya +5 more
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Proteome Profiling of Leishmania Infantum Promastigotes
Journal of Eukaryotic Microbiology, 2011 ABSTRACT. A proteome analysis of the promastigote stage of the trypanosomatid parasite Leishmania infantum (MON‐1 zymodeme) is described here for the first time. Total protein extracts were prepared at early logarithmic and stationary phases of replicate axenic cultures and processed by 2D electrophoresis (pH 3–10).
Alcolea, Pedro J. +2 more
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Genome Plasticity in Cultured Leishmania donovani: Comparison of Early and Late Passages
Frontiers in Microbiology, 2018 Leishmania donovani possesses a complex heteroxenic life cycle where infective metacyclic promastigotes are pre-adapted to infect their host and cope up with intracellular stress.
Roma Sinha +11 more
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Biomolecules, 2019 A series of seven chalcone-thiosemicarbazones (5a−5g) were synthesized and evaluated as potential new drugs (anti-leishmanial effect). Although four of the chalcone-thiosemicarbazones are already known, none of them or any compound in this class ...
Edinéia Pastro Mendes +7 more
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Critical Antileishmanial in vitro Effects of Highly Examined Gold Nanoparticles
International Journal of Nanomedicine, 2021 Muzamil Yaqub Want,1,2 Priya Yadav,1,3 Rakin Khan,1 Garima Chouhan,1,4 Mohammad Islamuddin,1,5 Sheka Yagub Aloyouni,6 Asoke P Chattopadhyay,7 Suliman Yousef AlOmar,8 Farhat Afrin1,9 1Parasite Immunology Laboratory, Department of Biotechnology, Jamia ...
Want MY +8 more
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