Results 81 to 90 of about 7,503 (174)

Inhibition of pteridine reductase 1 (PTR1) expression in Leishmania promastigotes using a full-length antisense construct

open access: yes, 2009
Leishmania exhibit many unusual features, one of which is the pteridine metabolic pathway essential for the growth for these parasites. Leishmania have evolved a complex and versatile pteridine salvage network capable of scavenging a wide array of ...
Nariman Mosaffa   +7 more
core  

LiEndoG single allele replacement reduces L. infantum promastigotes growth rate.

open access: yes, 2014
A) Immuno-blot using the monoclonal antibody α-rLiEndoG against cellular extracts from wild-type (WT) promastigotes and from two clones of L. infantum promastigotes with a single copy of the LiEndoG gene: SKOendoG(2) and SKOendoG(6). A Polyclonal α-Hsp70
Alba Gigante (527991)   +12 more
core   +1 more source

Evidence of RNA editing in Leishmania braziliensis promastigotes

open access: yesParasitology Research, 2010
RNA editing in trypanosomatids is an elaborate form of post-transcriptional processing that inserts and deletes uridines in many mitochondrial pre-mRNAs, providing the genetic information needed to create functional transcripts. The process has been extensively analyzed in Trypanosoma brucei, Crithidia fasciculata, and Leishmania tarentolae.
Ramírez, César A.   +2 more
openaire   +3 more sources

Export of miRNAs from activated macrophages is cooperative and HuR‐dependent

open access: yesFEBS Letters, Volume 600, Issue 5, Page 693-709, March 2026.
This study uncovers a new mechanism for miRNA export regulation in mammalian cells, driven by the RNA‐binding protein HuR. In macrophages, HuR cooperatively binds with miRNAs to export both low‐ and high‐affinity substrates, thereby influencing macrophage activation.
Syamantak Ghosh   +2 more
wiley   +1 more source

Scanning electron microscopy of promastigotes treated with KalsomeTM10.

open access: yes, 2017
Promastigotes were either left untreated (a) or treated with 5.0 μg/ml of Kalsome TM10 (b) for 2 h and then analysed for surface topology. SEM micrographs show rounded and distorted shape in KalsomeTM10 treated promastigotes compared to controls.
Md. Shadab (1489078)   +5 more
core   +1 more source

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

open access: yesArchiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi   +17 more
wiley   +1 more source

The activity of extracts chara vulgaris against promastigotes of leishmania tropica.

open access: yesمجلة مركز بحوث التقنيات الاحيائية, 2018
            Leishmaniasis is a widespread parasitic disease caused by Leishmania parasite, this disease considers as a major health problem worldwide. The available therapy is unsatisfactory expensive with a cytotoxic side effects.
Ban Hussein Ali   +2 more
doaj   +1 more source

Percentage of viability of promastigotes to different concentrations of AmB.

open access: yes, 2018
Promastigotes of the reference strain for each species were selected by gradually increasing the AmB concentration. The dotted line graphs indicate the less sensitive promastigotes.
Carlos Franco-Muñoz (751372)   +2 more
core   +1 more source

The role of surface glycoconjugates in Leishmania midgut attachment examined by competitive binding assays and experimental development in sand flies [PDF]

open access: yes, 2013
SUMMARY Binding of promastigotes to the sand fly midgut epithelium is regarded as an essential part of the Leishmania life cycle in the vector. Among Leishmania surface molecules putatively involved in attachment to the sand fly midgut, two GPI-anchored ...
Jecna, Lucie   +13 more
core   +1 more source

Inhibitory effects of Zanthoxylum rhoifolium Lam. (Rutaceae) against the infection and infectivity of macrophages by Leishmania amazonensis

open access: yesAnais da Academia Brasileira de Ciências, 2016
Zanthoxylum rhoifolium Lam. (Rutaceae) has been traditionally used in the treatment of microbial infections and parasitic diseases. In the present study, the antileishmanial effect induced by the ethanol extract of stem barks from Z. rhoifolium (ZR-EEtOH)
BERNARDO MELO NETO   +8 more
doaj   +1 more source

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