Results 1 to 10 of about 11,687 (117)
Macromolecular biosynthetic parameters and metabolic profile in different life stages of Leishmania braziliensis: Amastigotes as a functionally less active stage [PDF]
PLoS ONE, 2017 It was recently hypothesized that Leishmania amastigotes could constitute a semi-quiescent stage characterized by low replication and reduced metabolic activity.
Marlene Jara, Maya Berg, Guy Caljon
exaly +2 more sources
Trypanosoma cruzi extracellular amastigotes and host cell signaling: more pieces to the puzzle
Frontiers in Immunology, 2012 Among the different infective stages that Trypanosoma cruzi employs to invade cells, extracellular amastigotes have recently gained attention by our group.
Ferreira Eden R +2 more
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Frontiers in Cellular and Infection Microbiology, 2022 P21 is an immunomodulatory protein expressed throughout the life cycle of Trypanosoma cruzi, the etiologic agent of Chagas disease. In vitro and in vivo studies have shown that P21 plays an important role in the invasion of mammalian host cells and ...
Thaise Lara Teixeira +10 more
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Evaluation of the Photodynamic Therapy with Curcumin on L. braziliensis and L. major Amastigotes
Antibiotics, 2021 Cutaneous leishmaniasis (CL) is a neglected disease prevalent in tropical countries with the ability to cause skin lesions. Photodynamic therapy (PDT) represents a specific and topical option for the treatment of these lesions.
André Henrique Correia Pereira +3 more
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Investigation of in vitro Cytotoxicity of Chelidonium majus against Leishmania Major [PDF]
Archives of Razi Institute, 2022 One of the public health issues in the endemic areas, especially in the Middle East region would be the Leishmaniasis. The suggested cure for leishmaniasis is pentavalent antimonials.
K Madjeed Haddao +9 more
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Advances in Understanding Leishmania Pathobiology: What Does RNA-Seq Tell Us?
Frontiers in Cell and Developmental Biology, 2021 Leishmaniasis is a vector-borne disease caused by a protozoa parasite from over 20 Leishmania species. The clinical manifestations and the outcome of the disease vary greatly.
Tamara Salloum +2 more
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 A rational-based process was adopted for repurposing pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs bearing variable acyl chains, different stereochemical configuration and/or positional relationships.
Ahmed H. E. Hassan +7 more
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Frontiers in Cellular and Infection Microbiology, 2022 Leishmania is the unicellular parasite transmitted by phlebotomine sand fly bite. It exists in two different forms; extracellular promastigotes, occurring in the gut of sand flies, and intracellular, round-shaped amastigotes residing mainly in vertebrate
Lenka Pacakova +4 more
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Characterization of in Vitro Cultivated Amastigote like of Leishmania major: A Substitution for in Vivo Studies [PDF]
Iranian Journal of Parasitology, 2008 Background: Promastigotes of Leishmania spp. have been readily cultured, but the axenic culture of amastigotes has been successful in L. donovani, L .infantum L. mexicana and L. pifanoi. However, some species such as L.
P Habibi +7 more
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Trypanocidal Activity of Long Chain Diamines and Aminoalcohols
Molecules, 2015 Thirteen aminoalcohols and eight diamines were obtained and tested against Trypanosoma cruzi epimastigotes strains MG, JEM and CL-B5 clone. Some of them were equal or more potent (1.0–6.6 times) than the reference compound nifurtimox.
Ana L. Legarda-Ceballos +9 more
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