Results 1 to 10 of about 5,108 (120)
Molecules, 2021 Five heteroleptic compounds, [VVO(IN-2H)(L-H)], where L are 8-hydroxyquinoline derivatives and IN is a Schiff base ligand, were synthesized and characterized in both the solid and solution state.
Gonzalo Scalese +4 more
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Frontiers in Immunology, 2023 American trypanosomiasis, or Chagas disease, is caused by the protozoan parasite Trypanosoma cruzi and is characterized by the presence of cardiac or gastrointestinal symptoms in a large number of patients during the chronic phase of the disease ...
Alberto Cornet-Gomez +5 more
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Transcriptomic changes across the life cycle of Trypanosoma cruzi II [PDF]
PeerJ, 2020 Trypanosoma cruzi is a flagellated protozoan that causes Chagas disease; it presents a complex life cycle comprising four morphological stages: epimastigote (EP), metacyclic trypomastigote (MT), cell-derived trypomastigote (CDT) and amastigote (AM ...
Lissa Cruz-Saavedra +3 more
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Frontiers in Cellular and Infection Microbiology, 2021 Trypanosoma cruzi, the etiological agent of Chagas disease in humans, infects a wide variety of vertebrates. Trypomastigotes, the parasite infective forms, invade mammalian cells by a still poorly understood mechanism. Adhesion of tissue culture- derived
Nubia Carolina Manchola Varón +3 more
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Molecular basis of mammalian cell invasion by Trypanosoma cruzi
Anais da Academia Brasileira de Ciências, 2006 Establishment of infection by Trypanosoma cruzi, the agent of Chagas' disease, depends on a series of events involving interactions of diverse parasite molecules with host components.
Nobuko Yoshida
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Mammalian cell invasion and intracellular trafficking by Trypanosoma cruzi infective forms
Anais da Academia Brasileira de Ciências, 2005 Trypanosoma cruzi, the etiological agent of Chagas’ disease, occurs as different strains or isolates that may be grouped in two major phylogenetic lineages: T. cruzi I, associated with the sylvatic cycle and T. cruzi II, linked to the human disease.
Renato A. Mortara +7 more
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Memorias do Instituto Oswaldo Cruz, 2009 Since the discovery of Trypanosoma cruzi and the brilliant description of the then-referred to "new tripanosomiasis" by Carlos Chagas 100 years ago, a great deal of scientific effort and curiosity has been devoted to understanding how this parasite ...
Maria Julia Manso Alves +1 more
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Memorias do Instituto Oswaldo Cruz, 1987 Megazol, nifurtimox, benznidazol and allopurinol were investigated, by light and electron µscopy, for their action on T. cruzi. Both the direct effect upon amastigote and trypomastigote forms and the effect upon the interaction of heart muscle cells (HMC)
Solange L. de Castro +1 more
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Memorias do Instituto Oswaldo Cruz, 2009 In previous work, we proposed alternative protocols for following patients with treated Chagas disease and these are reviewed herein. Evidence was provided to support the following: (i) functional anti-trypomastigote antibodies are indicative of ongoing ...
Antoniana Ursine Krettli
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Influence of Ecto-nucleoside triphosphate diphosphohydrolase activity on Trypanosoma cruzi infectivity and virulence. [PDF]
PLoS Neglected Tropical Diseases, 2009 BACKGROUND: The protozoan Trypanosoma cruzi is the causative agent of Chagas disease. There are no vaccines or effective treatment, especially in the chronic phase when most patients are diagnosed.
Ramon F Santos +8 more
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