Results 61 to 70 of about 7,503 (174)

Isolation of metacyclic promastigotes from the sand fly gut.

, 2019
(A) Promastigote stages during development within the sand fly gut. Adapted from [14]. (B) Location of metacyclic promastigotes in the anterior pole of the PSG-promastigote plug in contact with the SV. Reproduced from [7].
Maribel Jiménez (22374), Ana Alonso (673057), Peter J. Myler (244412), Pedro J. Alcolea (553038), Ricardo Molina (505031), Vicente Larraga (238914)   +5 more
core   +1 more source

Rapid phagosome formation drives parasite control in subclinical Leishmania braziliensis infection

Frontiers in Immunology
IntroductionCutaneous leishmaniasis (CL) caused by Leishmania braziliensis displays a wide spectrum of clinical manifestations characterized by an inflammatory Th1 response that leads to the development of skin lesions.
Caic Figueiredo, Alan Rocha dos Santos, Camila Pimentel, Maurício T. Nascimento, Maurício T. Nascimento, Fabio Peixoto, Fabio Peixoto, Vítor Oliveira, Olivia Bacellar, Olivia Bacellar, Lucas P. Carvalho, Lucas P. Carvalho, Lucas P. Carvalho, Edgar M. Carvalho, Edgar M. Carvalho, Edgar M. Carvalho, Thiago M. Cardoso, Thiago M. Cardoso, Thiago M. Cardoso   +18 more
doaj   +1 more source

Peptides as a Therapeutic Alternative Against Leishmaniasis: A Scoping Review

Chemical Biology &Drug Design, Volume 107, Issue 5, May 2026.
This scoping review of 79 studies identified 231 antimicrobial peptides with anti‐Leishmania activity, including natural‐derived and synthetic peptides (inspired by natural sources or developed through rational design). Most were evaluated in vitro against promastigote and/or amastigote forms, with synthetic peptides showing a more promising effect ...
Maria Eduarda da Veiga Oliveira, Ellen Dyminski Parente Ribeiro, Otávio Henrique Pradi Guenther, Fernanda Tomiotto‐Pellissier   +3 more
wiley   +1 more source

Leishmania donovani metacyclic promastigotes impair phagosome properties in inflammatory monocytes [PDF]

, 2021
Leishmaniasis, a debilitating disease with clinical manifestations ranging from self-healing ulcers to life-threatening visceral pathologies, is caused by protozoan parasites of the Leishmania genus.
Matte, Christine, Descoteaux, Albert, Arango Duque, Guillermo   +2 more
core   +1 more source

Effects of Methanolic Extract of Arctium lappa Root on Promastigotes and Amastigotes of Leishmania major (in vitro)

Medical Laboratory Journal, 2016
Background and Objective: Leishmania major is a flagellate protozoan parasite causing cutaneous leishmaniasis. Although pentavalent antimony compounds are the first-line drugs for leishmaniasis, their application is often accompanied by numerous ...
Asghar Farghi Yamchi, Mansour Dabirzadeh, Abdolhossein Miri   +2 more
doaj  

Knowledge mapping of risk mitigation measures against vector‐borne diseases

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract A comprehensive synthesis of current evidence on surveillance, prevention and control measures for 25 selected vector‐borne diseases (VBDs) affecting animals in the EU is presented here. The assessment integrates evidence from systematic literature reviews, modelling studies, field investigations and expert judgement.
European Food Safety Authority (EFSA), Ieva Baltusyte, Fabio Bigoni, Alessandro Broglia, Sofie Dhollander, Stefania Tampach, Jordi Figuerola, Hans Hermann Thulke, Miguel Ángel Chueca Miranda   +8 more
wiley   +1 more source

Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa.

, 2005
In this paper we describe the preparation of some biphenylquinuclidine derivatives and their evaluation as inhibitors of squalene synthase in order to explore their potential in the treatment of the parasitic diseases leishmaniasis and Chagas disease ...
Croft, Simon L, Cammerer, Simon, Gilbert, Ian H, Orenes Lorente, Silvia, Ruiz Perez, Luis M, Urbina, Julio, Gonzalez Pacanowska, Dolores, Jiménez, Carmen, Pacanowska, Dolores Gonzalez, de Luca-Fradley, Kate, Gómez, Rosario, Perez, Luis M. Ruiz, Gilbert, Ian H., Lorente, Silvia Orenes, Yardley, Vanessa, Croft, Simon L.   +15 more
core   +1 more source

Vector‐borne diseases‐knowledge maps

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract This scientific report provides a structured overview of the main characteristics of 25 selected vector‐borne diseases (VBDs) of potential relevance for the EU, including 12 diseases listed under the Animal Health Law (AHL) and 13 non‐listed diseases.
European Food Safety Authority (EFSA), Sofie Dhollander, Ieva Baltusyte, Fabio Bigoni, Alessandro Broglia, Jordi Figuerola, Hans‐Hermann Thulke, Miguel Angel Chueca Miranda   +7 more
wiley   +1 more source

Antimicrobial Peptides and Their Anti-Leishmanial Efficacies on Leishmania tropica Promastigotes In vitro [PDF]

Objective: Antimicrobial resistance is a real threat to humanity. Pentavalent antimonials are reported non-effective in leishmaniasis treatment today, in countries like India. New treatment options have been assessed worldwide lately.
İbrahim Çavuş, Ahmet Özbilgin, Tanıl Kocagöz, Tuba Polat, Nihan Ünübol, Özgür Kurt   +5 more
core   +1 more source

Response of Leishmania chagasi promastigotes to oxidant stress [PDF]

Infection and Immunity, 1994
At the onset of infection, Leishmania promastigotes are phagocytized by mammalian macrophages. They must survive despite exposure to toxic oxidants such as hydrogen peroxide (H2O2) and superoxide (.O2-) generated during phagocytosis. We investigated the effects of these oxidants on Leishmania chagasi promastigotes and promastigote mechanisms for ...
M E, Wilson, K A, Andersen, B E, Britigan   +2 more
openaire   +2 more sources