An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones [PDF]
Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Ore reporter mouse system in
Arthur, J.+6 more
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MhYTP1 and MhYTP2 from Apple Confer Tolerance to Multiple Abiotic Stresses in Arabidopsis thaliana
The first YTH domain-containing RNA binding protein (YTP) was found in rat, where it was related to oxidative stress. Unlike characterizations in yeast and animals, functions of plant YTPs are less clear. Malus hupehensis (Pamp.) Rehd.
Na Wang+8 more
doaj +1 more source
Survivin a radiogenetic promoter for glioblastoma viral gene therapy independently from CArG motifs [PDF]
BACKGROUND: Radiogenetic therapy is a novel approach in the treatment of cancer, which employs genetic modification to alter the sensitivity of tumor cells to the effect of applied radiation.
Arafat WO+16 more
core +2 more sources
c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic Cells. [PDF]
ObjectiveADAMTS (a disintegrin and metalloproteinase with thrombospondin type-1 motif) zinc metalloproteinases are important during the synthesis and breakdown of cartilage extracellular matrix.
Amanatullah, Derek F+4 more
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ArgR is an essential local transcriptional regulator of the arcABC-operon in Streptococcus suis and crucial for biological fitness in acidic environment [PDF]
Streptococcus suis is one of the most important pathogens in pigs and can also cause severe infections in humans. Despite its clinical relevance very little is known about the factors contributing to its virulence.
Benga, L.+6 more
core +2 more sources
The question is not whether to promote or not to promote, but rather when to promote
Abstract The Klein Karoo National Arts Festival (KKNK) is one of South Africa's largest and most popular arts festivals. The success of the festival is dependent on the number of tickets sold. Therefore, in order to ensure an increase in ticket sales, the festival organisers/marketers need to know how long before the event visitors decide to attend the
Kruger, Martinette, Saayman, Melville
openaire +3 more sources
AIM: To investigate the association between apolipoprotein E (APOE) -219 T>G promoter polymorphism and primary open angle glaucoma (POAG).METHODS: Patients and healthy subjects were genotyped with polymerase chain reaction-restriction fragment length ...
Emel Saglar, Banu Bozkurt, Murat Irkec
doaj +1 more source
اثر اصلاح کنند ه ها روی فعالیت کاتالیزورهای زیگلر-ناتا و خواص نهایی پلیمر در پلیمرشدن اولفین ها [PDF]
فعالیت کاتالیزور از مهم ترین پارامترها در فرایندهای پلیمرشدن است. برای یک سامانه کاتالیزوریفعالیت ممکن است به شرایط پلیمرشدن از قبیل دما و فشار وابسته باشد.
رضا بازوند+3 more
doaj +1 more source
Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors
Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases.
Bradley S. Hollidge+9 more
doaj +1 more source
The formation mechanism underlying the blue eggshell characteristic has been discovered in birds, and SLCO1B3 is the key gene that regulates the blue eggshell color.
Zhuanjian Li+20 more
doaj +1 more source