Results 1 to 10 of about 588,002 (199)
Current Issues in Molecular Biology, 2021 DNA methylation and the alternative splicing of precursor messenger RNAs (pre-mRNAs) are two important genetic modification mechanisms. However, both are currently uncharacterized in the muscle metabolism of rabbits. Thus, we constructed the Tianfu black
Yanhong Li +10 more
doaj +1 more source
Synthetic biology: advancing biological frontiers by building synthetic systems [PDF]
, 2012 Advances in synthetic biology are contributing to diverse research areas, from basic biology to biomanufacturing and disease therapy.
Chen, Yvonne Y. +2 more
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Epigenetic transgenerational actions of vinclozolin on promoter regions of the sperm epigenome.
PLoS ONE, 2010 Previous observations have demonstrated that embryonic exposure to the endocrine disruptor vinclozolin during gonadal sex determination promotes transgenerational adult onset disease such as male infertility, kidney disease, prostate disease, immune ...
Carlos Guerrero-Bosagna +3 more
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Interaction between non-coding RNAs, mRNAs and G-quadruplexes
Cancer Cell International, 2022 G-quadruplexes are secondary helical configurations established between guanine-rich nucleic acids. The structure is seen in the promoter regions of numerous genes under certain situations.
Soudeh Ghafouri-Fard +6 more
doaj +1 more source
Promoter trapping in microalgae using the antibiotic paromomycin as selective agent [PDF]
, 2012 The lack of highly active endogenous promoters to drive the expression of transgenes is one of the main drawbacks to achieving efficient transformation of many microalgal species.
Díaz Santos, Encarnación +5 more
core +3 more sources
Construction and characterization of a synthetic Baculovirus-inducible 39K promoter
Journal of Biological Engineering, 2018 Background Silkworm genetic engineering is widely used in gene function, silk engineering and disease-resistant engineering in most of Asia. Some of the earliest promoter elements are used to control the development of silkworm transgenic expression and ...
Zhan-Qi Dong +7 more
doaj +1 more source
A sigma factor toolbox for orthogonal gene expression in Escherichia coli [PDF]
, 2018 Synthetic genetic sensors and circuits enable programmable control over timing and conditions of gene expression and, as a result, are increasingly incorporated into the control of complex and multi-gene pathways.
Bervoets, Indra +6 more
core +4 more sources
Journal of Plant Protection Research, 2021 β-1,3-glucanases play a major role in combating the abnormal leaf fall disease (ALF) caused by the oomycete Phytophthora spp. in Hevea brasiliensis, the major commercial source of natural rubber. In this study, partial sequences of four novel promoters
Supriya Radhakrishnan +3 more
doaj +1 more source
Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients. [PDF]
, 2018 OBJECTIVE:Epigenetic modifications have previously been associated with rheumatoid arthritis (RA). In this study, we aimed to determine whether differential DNA methylation in peripheral blood cell subpopulations is associated with any of 4 clinical ...
Barcellos, Lisa F +13 more
core +1 more source
SUVH1, a Su(var)3-9 family member, promotes the expression of genes targeted by DNA methylation. [PDF]
, 2015 Transposable elements are found throughout the genomes of all organisms. Repressive marks such as DNA methylation and histone H3 lysine 9 (H3K9) methylation silence these elements and maintain genome integrity.
Chen, Xuemei +6 more
core +2 more sources