Functional Characterization of Genetic Polymorphisms Identified in the Promoter Region of the Bovine PEPS Gene [PDF]
DNA and Cell Biology, 2012 Peptidase S (PEPS) is a metallopeptidase that cleaves N -terminal residues from proteins and peptides. PEPS is used as a cell maintenance enzyme with critical roles in peptide turnover. The promoter region located upstream of the initiation site plays an important role in regulating gene ...
Zhihua, Ju +7 more
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The 5' untranslated region of the I factor, a long interspersed nuclear element-like retrotransposon of Drosophila melanogaster, contains an internal promoter and sequences that regulate expression [PDF]
, 1993 The I-R system of hybrid dysgenesis in Drosophila melanogaster is controlled by a long interspersed nuclear element-like retroposon, the I factor.
FINNEGAN, D J +3 more
core +1 more source
Mechanisms underlying the tissue-specific and regulated activity of the Gnrhr promoter in mammals.
Frontiers in Endocrinology, 2012 The GnRH receptor (GnRHR) plays a central role in the development and maintenance of reproductive function in mammals. Following stimulation by GnRH originating from the hypothalamus, GnRHR triggers multiple signalling events that ultimately stimulate ...
Anne-Laure eSchang +7 more
doaj +1 more source
Investigation of XvSap promoters from the resurrection plant, Xerophyta viscosa [PDF]
, 2012 Includes bibliographical references.The XvPSap1 promoter derived from Xerophyta viscosa has been demonstrated to be stress-inducible during dehydration in transgenic Nicotiana tabacum, black Mexican sweetcorn cells and Zea mays. To improve this promoter,
Ellick, Tamaryn Lorean
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Positive selection in coding regions and motif duplication in regulatory regions of bottlenose dolphin MHC class II genes. [PDF]
PLoS ONE, 2018 The vertebrate immune response is mediated through highly adaptive, quickly evolving cell surface receptors, the major histocompatibility complex (MHC).
Heidi J T Pagán +2 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Genetic Dissection of the Light-InduciblecarQRSPromoter Region ofMyxococcus xanthus [PDF]
Journal of Bacteriology, 2004 ABSTRACTInMyxococcus xanthusphotoprotective carotenoids are produced in response to illumination due to regulated expression of carotenoid biosynthesis genes at two loci. Induction of the carotenogenesis regulon is dependent on expression of thecarQRSoperon.
David E, Whitworth +4 more
openaire +2 more sources
Synthesis of a HDC-GFP Promoter-Gene Fusion as a Tool to Identify Histaminergic Cells and Examine HDC Regulation [PDF]
, 2007 The promoter region for the Histidine decarboxylase gene (pHdc), which is required for synthesis of the neurotransmitter histamine, has been functionally identified in Drosophila melanogaster.
Anderson, Erik R
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source