Identification of Minimal p53 Promoter Region Regulated by MALAT1 in Human Lung Adenocarcinoma Cells
Frontiers in Genetics, 2018 The MALAT1 long noncoding RNA is strongly linked to cancer progression. Here we report a MALAT1 function in repressing the promoter of p53 (TP53) tumor suppressor gene.
Keiko Tano +6 more
doaj +1 more source
Variation in the flowering time orthologs BrFLC and BrSOC1 in a natural population of Brassica rapa. [PDF]
, 2015 Understanding the genetic basis of natural phenotypic variation is of great importance, particularly since selection can act on this variation to cause evolution.
Franks, Steven J +7 more
core +2 more sources
Statistically Significant Strings are Related to Regulatory Elements in the Promoter Regions of Saccharomyces cerevisiae [PDF]
, 2000 Finding out statistically significant words in DNA and protein sequences forms the basis for many genetic studies. By applying the maximal entropy principle, we give one systematic way to study the nonrandom occurrence of words in DNA or protein ...
Bin Wang +17 more
core +2 more sources
Polimorfismos en el gen promotor de IL-10 en una muestra de pacientes colombianos con lepra
Biomédica: revista del Instituto Nacional de Salud, 2012 Introducción. Se han reportado polimorfismos en los genes promotores que codifican para citocinas y que afectan los niveles de transcripción, con implicaciones clínicas y funcionales en pacientes con lepra. Objetivo.
Nora Cardona-Castro +3 more
doaj +1 more source
A sigma factor toolbox for orthogonal gene expression in Escherichia coli [PDF]
, 2018 Synthetic genetic sensors and circuits enable programmable control over timing and conditions of gene expression and, as a result, are increasingly incorporated into the control of complex and multi-gene pathways.
Bervoets, Indra +6 more
core +4 more sources
Stress-induced duplex destabilization (SIDD) profiles for T7 bacteriophage promoters [PDF]
Компьютерные исследования и моделирование, 2018 The functioning of DNA regulatory regions rely primarily on their physicochemical and structural properties but not on nucleotide sequences, i.e. genetic text.
Mikhail Anatolievich Orlov +4 more
doaj +1 more source
Genetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget's disease of bone [PDF]
, 2012 We performed a genetic association study of rare variants and single nucleotide polymorphisms (SNPs) of UCMA/GRP and OPTN genes, in French-Canadian patients with Paget's disease of bone (PDB) and in healthy controls from the same population.
Albagha +41 more
core +1 more source
Genetic analysis of the dsz promoter and associated regulatory regions of Rhodococcus erythropolis IGTS8 [PDF]
Journal of Bacteriology, 1996 The dsz gene cluster of Rhodococcus erythropolis IGTS8 comprises three genes, dszA, dszB, and dszC, whose products are involved in the conversion of dibenzothiophene (DBT) to 2-hydroxybiphenyl and sulfite. This organism can use DBT as the sole sulfur source but not as a carbon source.
M Z, Li +3 more
openaire +2 more sources
Current Issues in Molecular Biology, 2021 DNA methylation and the alternative splicing of precursor messenger RNAs (pre-mRNAs) are two important genetic modification mechanisms. However, both are currently uncharacterized in the muscle metabolism of rabbits. Thus, we constructed the Tianfu black
Yanhong Li +10 more
doaj +1 more source
Genetic Polymorphism of the Nrf2 Promoter Region (rs35652124) Is Associated with the Risk of Diabetic Foot Ulcers [PDF]
Oxidative Medicine and Cellular Longevity, 2020 The genetic polymorphism in the nuclear factor erythroid 2-related factor 2 (Nrf2) gene has been reported as one of the prognosis markers for various diseases, including cancer. Nrf2 is a key transcription factor involved in wound healing by regulating angiogenesis.
Rajan Teena +4 more
openaire +2 more sources