urg1: A Uracil-Regulatable Promoter System for Fission Yeast with Short Induction and Repression Times [PDF]
Background. The fission yeast Schizosaccharomyces pombe is a popular genetic model organism with powerful experimental tools. The thiamine-regulatable nmt1 promoter and derivatives, which take > 15 hours for full induction, are most commonly used for ...
Mata, J +23 more
core +1 more source
Identification of Minimal p53 Promoter Region Regulated by MALAT1 in Human Lung Adenocarcinoma Cells
The MALAT1 long noncoding RNA is strongly linked to cancer progression. Here we report a MALAT1 function in repressing the promoter of p53 (TP53) tumor suppressor gene.
Keiko Tano +6 more
doaj +1 more source
Evolution of the leukotoxin promoter in genus Mannheimia [PDF]
<b>Background</b>: The <i>Mannheimia</i> species encompass a wide variety of bacterial lifestyles, including opportunistic pathogens and commensals of the ruminant respiratory tract, commensals of the ovine rumen, and pathogens of
Pedersen, A.G. +35 more
core +2 more sources
Polimorfismos en el gen promotor de IL-10 en una muestra de pacientes colombianos con lepra
Introducción. Se han reportado polimorfismos en los genes promotores que codifican para citocinas y que afectan los niveles de transcripción, con implicaciones clínicas y funcionales en pacientes con lepra. Objetivo.
Nora Cardona-Castro +3 more
doaj +1 more source
Functional analysis of human and chimpanzee promoters [PDF]
Background: It has long been argued that changes in gene expression may provide an additional and crucial perspective on the evolutionary differences between humans and chimpanzees.
Philipp Khaitovich +21 more
core +1 more source
Stress-induced duplex destabilization (SIDD) profiles for T7 bacteriophage promoters [PDF]
The functioning of DNA regulatory regions rely primarily on their physicochemical and structural properties but not on nucleotide sequences, i.e. genetic text.
Mikhail Anatolievich Orlov +4 more
doaj +1 more source
Genetic analysis of the dsz promoter and associated regulatory regions of Rhodococcus erythropolis IGTS8 [PDF]
The dsz gene cluster of Rhodococcus erythropolis IGTS8 comprises three genes, dszA, dszB, and dszC, whose products are involved in the conversion of dibenzothiophene (DBT) to 2-hydroxybiphenyl and sulfite. This organism can use DBT as the sole sulfur source but not as a carbon source.
M Z, Li +3 more
openaire +2 more sources
MDM2 negatively regulates the human telomerase RNA gene promoter [PDF]
<b>Background:</b> We have previously demonstrated that NF-Y and Sp1 interact with the human telomerase RNA (hTR) promoter and play a central role in its regulation. We have also shown that pRB activates the hTR promoter, but the mechanism
Jiangqin Zhao (6471) +15 more
core +2 more sources
DNA methylation and the alternative splicing of precursor messenger RNAs (pre-mRNAs) are two important genetic modification mechanisms. However, both are currently uncharacterized in the muscle metabolism of rabbits. Thus, we constructed the Tianfu black
Yanhong Li +10 more
doaj +1 more source
Epigenetic transgenerational actions of vinclozolin on promoter regions of the sperm epigenome.
Previous observations have demonstrated that embryonic exposure to the endocrine disruptor vinclozolin during gonadal sex determination promotes transgenerational adult onset disease such as male infertility, kidney disease, prostate disease, immune ...
Carlos Guerrero-Bosagna +3 more
doaj +1 more source

