Statistically Significant Strings are Related to Regulatory Elements in the Promoter Regions of Saccharomyces cerevisiae [PDF]
, 2000 Finding out statistically significant words in DNA and protein sequences forms the basis for many genetic studies. By applying the maximal entropy principle, we give one systematic way to study the nonrandom occurrence of words in DNA or protein ...
Bin Wang +17 more
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Genetic analysis of the dsz promoter and associated regulatory regions of Rhodococcus erythropolis IGTS8 [PDF]
Journal of Bacteriology, 1996 The dsz gene cluster of Rhodococcus erythropolis IGTS8 comprises three genes, dszA, dszB, and dszC, whose products are involved in the conversion of dibenzothiophene (DBT) to 2-hydroxybiphenyl and sulfite. This organism can use DBT as the sole sulfur source but not as a carbon source.
M Z, Li +3 more
openaire +2 more sources
Polimorfismos en el gen promotor de IL-10 en una muestra de pacientes colombianos con lepra
Biomédica: revista del Instituto Nacional de Salud, 2012 Introducción. Se han reportado polimorfismos en los genes promotores que codifican para citocinas y que afectan los niveles de transcripción, con implicaciones clínicas y funcionales en pacientes con lepra. Objetivo.
Nora Cardona-Castro +3 more
doaj +1 more source
Screening of the transcriptional regulatory regions of vascular endothelial growth factor receptor 2 (VEGFR2) in amyotrophic lateral sclerosis [PDF]
, 2007 Background Vascular endothelial growth factor (VEGF) has neurotrophic activity which is mediated by its main agonist receptor, VEGFR2. Dysregulation of VEGF causes motor neurone degeneration in a mouse model of amyotrophic lateral sclerosis (ALS), and
Brockington, A. +4 more
core +3 more sources
Genetic Variants in the Promoter Region of miR-10b and the Risk of Breast Cancer [PDF]
BioMed Research International, 2017 Variants in microRNA genes may affect their expression by interfering with the microRNA maturation process and may substantially contribute to the risk of breast cancer. Recent studies have identified miR-10b as an interesting candidate because of its close association with the metastatic behavior of breast cancer. However, the roles of miR-10b-related
Jiaping Chen +9 more
openaire +2 more sources
Stress-induced duplex destabilization (SIDD) profiles for T7 bacteriophage promoters [PDF]
Компьютерные исследования и моделирование, 2018 The functioning of DNA regulatory regions rely primarily on their physicochemical and structural properties but not on nucleotide sequences, i.e. genetic text.
Mikhail Anatolievich Orlov +4 more
doaj +1 more source
Genetic Factors Contributing to the Susceptibility of Development of Prion Diseases [PDF]
, 2017 This paper won an honorable mention writing flag award in the research category. Claire Culbertson, writing for Katherine Bruner’s BIO 325L class, “Lab Experience in Genetics”.Bruner, KatherineUndergraduate ...
Culbertson, Claire
core +1 more source
Current Issues in Molecular Biology, 2021 DNA methylation and the alternative splicing of precursor messenger RNAs (pre-mRNAs) are two important genetic modification mechanisms. However, both are currently uncharacterized in the muscle metabolism of rabbits. Thus, we constructed the Tianfu black
Yanhong Li +10 more
doaj +1 more source
Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and Non-Hispanic Whites [PDF]
, 2009 BACKGROUND. Variations in gene allele frequencies can contribute to differences in the prevalence of some common complex diseases among populations. Natural selection modulates the balance in allele frequencies across populations.
Adiconis, Xian +9 more
core +3 more sources
Epigenetic transgenerational actions of vinclozolin on promoter regions of the sperm epigenome.
PLoS ONE, 2010 Previous observations have demonstrated that embryonic exposure to the endocrine disruptor vinclozolin during gonadal sex determination promotes transgenerational adult onset disease such as male infertility, kidney disease, prostate disease, immune ...
Carlos Guerrero-Bosagna +3 more
doaj +1 more source