β-1,3-glucanases play a major role in combating the abnormal leaf fall disease (ALF) caused by the oomycete Phytophthora spp. in Hevea brasiliensis, the major commercial source of natural rubber. In this study, partial sequences of four novel promoters
Supriya Radhakrishnan+3 more
doaj +1 more source
Genetic Alteration of p16INKA4A Promoter Region in Endometrial Carcinoma
Objective : This study was performed to evaluate the status of p16 tumor suppressor gene in 25 endometrial carcinomas (ECs) and to correlate the loss of heterozygosity (LOH) at p16 locus, the presence of inactivating mutations, the methylation status of the promotor, and the expression of p16 protein with clinicopathological parameters.
Se Jin Kim+7 more
openaire +2 more sources
Genetic Dissection of the Light-InduciblecarQRSPromoter Region ofMyxococcus xanthus [PDF]
ABSTRACTInMyxococcus xanthusphotoprotective carotenoids are produced in response to illumination due to regulated expression of carotenoid biosynthesis genes at two loci. Induction of the carotenogenesis regulon is dependent on expression of thecarQRSoperon.
David A. Hodgson+4 more
openaire +3 more sources
Construction and characterization of a synthetic Baculovirus-inducible 39K promoter
Background Silkworm genetic engineering is widely used in gene function, silk engineering and disease-resistant engineering in most of Asia. Some of the earliest promoter elements are used to control the development of silkworm transgenic expression and ...
Zhan-Qi Dong+7 more
doaj +1 more source
Genetic drift at expanding frontiers promotes gene segregation [PDF]
Competition between random genetic drift and natural selection plays a central role in evolution: Whereas non-beneficial mutations often prevail in small populations by chance, mutations that sweep through large populations typically confer a selective advantage.
arxiv +1 more source
Flexible Dynamics of Two Quorum Sensing Coupled Repressilators [PDF]
Genetic oscillators play important roles in cell life regulation. The regulatory efficiency usually depends strongly on the emergence of stable collective dynamic modes, which requires designing the interactions between genetic networks. We investigate the dynamics of two identical synthetic genetic repressilators coupled by an additional plasmid which
arxiv +1 more source
Positive selection in coding regions and motif duplication in regulatory regions of bottlenose dolphin MHC class II genes. [PDF]
The vertebrate immune response is mediated through highly adaptive, quickly evolving cell surface receptors, the major histocompatibility complex (MHC).
Heidi J T Pagán+2 more
doaj +1 more source
An Experimental-Design Perspective on Population Genetic Variation [PDF]
We consider the hypothesis that Evolution promotes population-wide genome patterns that, under randomization, ensures the External Validity of adaptations across population members. An adaptation is Externally Valid (EV) if its effect holds under a wide range of population genetic variations.
arxiv
Functional Characterization of Genetic Polymorphisms Identified in the Promoter Region of the BovinePEPSGene [PDF]
Peptidase S (PEPS) is a metallopeptidase that cleaves N-terminal residues from proteins and peptides. PEPS is used as a cell maintenance enzyme with critical roles in peptide turnover. The promoter region located upstream of the initiation site plays an important role in regulating gene expression.
Jifeng Zhong+7 more
openaire +3 more sources
Complementary Theory of Evolutionary Genetics [PDF]
This theory seeks to define species and to explore evolutionary forces and genetic elements in speciation and species maintenance. The theory explains how speciation and species maintenance are caused by natural selection acting on non-Mendelian and Mendelian variation, respectively. The emergence and maintenance of species as groups of populations are
arxiv