Results 81 to 90 of about 552,746 (191)
Scientific Reports, 2017 Aggregatibacter actinomycetemcomitans leukotoxin (LtxA) is a major virulence factor that kills leukocytes permitting it’s escape from host immune surveillance. A. actinomycetemcomitans strains can produce high or low levels of toxin.
Vandana Sampathkumar +3 more
doaj +1 more source
Genetic and Clinical Characteristics of Phyllodes Tumors of the Breast
Translational Oncology, 2018 PURPOSE: Phyllodes tumors (PTs) of the breast are rare, accounting for less than 1% of all breast tumors. Among PTs, malignant PTs (MPTs) have malignant characteristics and distant metastases occur in about 20% to 30% of MPTs.
Ji-Yeon Kim +10 more
doaj +1 more source
BioTechniques, 2008 System-oriented applications of genetic engineering, such as metabolic engineering, often require the serial optimization of enzymatic reaction steps, which can be achieved by transcriptional fine-tuning.
Stephan Braatsch +4 more
doaj +1 more source
Patterns of DNMT1 Promoter Methylation in Patients with Acute Lymphoblastic Leukemia
International Journal of Hematology-Oncology and Stem Cell Research, 2016 Background: Acute lymphoblastic leukemia (ALL) is a clonal malignant disorder characterized by an uncontrolled proliferation of immature T or B lymphocytes.
Tirdad Rahmani +5 more
doaj
Animal Biotechnology, 2012 Average daily gain (ADG) and feed efficiency (FE) are important factors for assessing productivity in farm animals. Myostatin (MSTN), previously called GDF8, is a member of transforming growth factor β (TGFβ) superfamily. It is a negative regulator for both embryonic development and adult homeostasis of skeletal muscle.
Jen-Wen Shiau +5 more
openaire +3 more sources
Expansion under climate change: the genetic consequences [PDF]
Bulletin of Mathematical Biology, Springer Verlag, 2016, 2016 Range expansion and range shifts are crucial population responses to climate change. Genetic consequences are not well understood but are clearly coupled to ecological dynamics that, in turn, are driven by shifting climate conditions. We model a population with a deterministic reaction-- diffusion model coupled to a heterogeneous environment that ...
arxiv
Prediction of Prokaryotic and Eukaryotic Promoters Using Convolutional Deep Learning Neural Networks [PDF]
arXiv, 2016 Accurate computational identification of promoters remains a challenge as these key DNA regulatory regions have variable structures composed of functional motifs that provide gene specific initiation of transcription. In this paper we utilize Convolutional Neural Networks (CNN) to analyze sequence characteristics of prokaryotic and eukaryotic promoters
arxiv
Multiple Attractor Cellular Automata (MACA) for Addressing Major Problems in Bioinformatics [PDF]
Review of Bioinformatics and Biometrics (RBB) Volume 2 Issue 3,
September 2013, 2013 CA has grown as potential classifier for addressing major problems in bioinformatics. Lot of bioinformatics problems like predicting the protein coding region, finding the promoter region, predicting the structure of protein and many other problems in bioinformatics can be addressed through Cellular Automata.
arxiv
Presence of recombination hotspots throughout SLC6A3.
PLoS ONE, 2019 The human dopamine transporter gene SLC6A3 is involved in substance use disorders (SUDs) among many other common neuropsychiatric illnesses but allelic association results including those with its classic genetic markers 3'VNTR or Int8VNTR remain mixed ...
Juan Zhao +5 more
doaj +1 more source
The genomic landscape of meiotic crossovers and gene conversions in Arabidopsis thaliana [PDF]
arXiv, 2013 Knowledge of the exact distribution of meiotic crossovers (COs) and gene conversions (GCs) is essential for understanding many aspects of population genetics and evolution, from haplotype structure and long-distance genetic linkage to the generation of new allelic variants of genes.
arxiv