Results 231 to 240 of about 136,204 (260)

Promyelocytic leukemia protein specifically augments the activation of NFAT (136.11)

The Journal of Immunology, 2009
Abstract Promyelocytic leukemia (PML) protein is a tumor suppressor with complicated action mechanisms not yet fully understood. Nuclear factor of activated T cells (NFAT) is an important factor for T cell functions. In this study, we found that PML specifically enhanced the transcription activation of NFAT.
Yu-Hsun Lo, Chia-Chen Wu, Hsiu-Ming Shih, Ming-Zong Lai   +3 more
openaire   +1 more source

Expression of granule protein mRNAs in acute promyelocytic leukemia.

Hematologic pathology, 1994
The granule proteins are among the most abundant and characteristic proteins of myeloid cells. They are essential for the antimicrobial activity of these cells and they provide important markers for the differentiation stage of the myeloid series and for the diagnosis of myeloid leukemias.
R K, Hirata, S T, Chen, S C, Weil
openaire   +1 more source

[Research advances on function of promyelocytic leukemia (PML) protein].

Ai zheng = Aizheng = Chinese journal of cancer, 2004
Through reviewing research advances on promyelocytic leukemia(PML) protein at home and abroad in recent years, the authors summarized the biological functions of PML protein in this paper. Recent researches indicated that all PML protein isoforms have RBCC (Ring finger domain, B-box, Coiled-Coil domain, RBCC)or TRIM (TRIpartite motif).
Peng-Cheng, He, Mei, Zhang, Fang, Wang
openaire   +1 more source

Interplay of protein misfolding pathway and unfolded-protein response in acute promyelocytic leukemia

Expert Review of Proteomics, 2010
Protein misfolding has traditionally been linked to the pathogenesis of various neurodegenerative diseases. However, emerging evidence from various laboratories, including ours, suggests that protein misfolding may also play a fundamental role in some malignancies, particularly those caused by fusion oncoprotein generated from chromosomal translocation.
openaire   +2 more sources

The PML-RARα Fusion Protein and Targeted Therapy for Acute Promyelocytic Leukemia

Leukemia & Lymphoma, 2004
Acute promyelocytic leukemia (APL) is an unique subtype of acute myeloid leukemia typically carrying a specific reciprocal chromosome translocation t(15;17) leading to the expression of a leukemia-generating fusion protein, PML-RARalpha. Nearly all de novo APL patients undergo disease remission when treated with all trans retinoic acid (ATRA) plus ...
openaire   +2 more sources

The RING domain of human promyelocytic leukemia protein (PML)

Journal of Biomolecular NMR, 2015
Shu-Yu, Huang, Chi-Fon, Chang, Pei-Ju, Fang, Mandar T, Naik, Peter, Güntert, Hsiu-Ming, Shih, Tai-Huang, Huang   +6 more
openaire   +2 more sources

Promyelocytic leukemia protein induces arsenic trioxide resistance through regulation of aldehyde dehydrogenase 3 family member A1 in hepatocellular carcinoma.

Cancer Letters, 2015
Xin Zhang, Xinrong Yang, Chao Sun, Bo Hu, Yunfan Sun, Xiaowu Huang, Zheng Wang, Yi-feng He, H. Zeng, S. Qiu, Ya Cao, Jia Fan, Jian Zhou   +12 more
semanticscholar   +1 more source

The contemporary management of cancers of the sinonasal tract in adults

Ca-A Cancer Journal for Clinicians, 2023
Rajat Thawani
exaly  

Annexin A2-S100A10 heterotetramer is upregulated by PML/RARα fusion protein and promotes plasminogen-dependent fibrinolysis and matrix invasion in acute promyelocytic leukemia

Frontiers in Medicine, 2017
Dan-yun Huang, Yan Yang, Jian Sun, Xiaorong Dong, Jiao Wang, Hong-chen Liu, Chengquan Lu, Xueyu Chen, Jing Shao, Jinsong Yan   +9 more
semanticscholar   +1 more source

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Victoria Metaxa, Elie Azoulay   +2 more
exaly