Results 211 to 220 of about 120,872 (251)

Management Challenges of Acute Promyelocytic Leukemia in Pregnancy: A Case Report. [PDF]

J Investig Med High Impact Case Rep
Hemry J, Shah P, Lee I, Dermarderosian A, Akhtari M.   +4 more
europepmc   +1 more source

Case report: <i>TTMV::RARA</i>-positive pediatric APL with spinal cord compression as initial presentation: unique clinical features and therapeutic outcomes revealed by a 12-case systematic cohort analysis. [PDF]

Front Oncol
Yang HL, Xin GY, Long MT, Chen D, Zhao X, Huang MJ, Yao ZL, Shen LQ, Ma JJ, Tuo YY, Li Y, Yang XY.   +11 more
europepmc   +1 more source

PML::RARA-negative APL-mimicking AML with a novel KMT2C::CREB3L2 fusion and RARA/RXRA-mediated sensitivity to all-trans retinoic acid. [PDF]

Ann Hematol
Ma L, Wu M.
europepmc   +1 more source

Asciminib and pulsed ATRA as post-remission therapy in T315I mutated PML-RARA-positive blast crisis of chronic myeloid leukemia. [PDF]

Ann Hematol
Mazzarella R, Cicconi L, Perrone S, Divona MD, Ceccolini S, Nardozza AM, Biagi A, Ottone T, Corbingi A, Panetta P, La Barbera EO, Fiori L, Romeo AA, Pacitto G, Cotroneo E, Breccia M, Voso MT, Pulsoni A.   +17 more
europepmc   +1 more source

Risk factors and management strategies in acute promyelocytic leukemia: a real-world single-center retrospective study. [PDF]

Front Med (Lausanne)
Jiang Y, Zhong H, Wang H, Tang D, Chen M, Peng H, Zhang G, Wang Y.   +7 more
europepmc   +1 more source

Primary Indolent Acute Promyelocytic Leukemia. [PDF]

Hematol Rep
Wolfenbarger B, Morera D, Wolfenbarger B, Jillella A, Zheng M.   +4 more
europepmc   +1 more source

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Promyelocytic leukemia protein: an atherosclerosis suppressor protein?

Clinical Science, 2021
As many as 70% of cells in atherosclerotic plaque are vascular smooth muscle cell (VSMC) in origin, and pathways and proteins which regulate VSMC migration, proliferation, and phenotype modulation represent novel targets for rational drug design to ...
Cali B. Corbett, Amanda St. Paul, M. Autieri   +2 more
semanticscholar   +3 more sources

Acute promyelocytic leukemia and variant fusion proteins: PLZF-RARα fusion protein at a glance

Seminars in Oncology, 2019
Classical acute promyelocytic leukemia (APL) cases are associated with the promyelocytic leukemia-retinoic acid receptor α (PML-RARα) chimeric fusion protein. Almost all the variant chimeric proteins share the same RARα component. Currently, more than 11
Liaqat Hussain, Yasen Maimaitiyiming, Hua Naranmandura   +2 more
exaly   +2 more sources

Promyelocytic Leukemia Protein, a Protein at the Crossroad of Oxidative Stress and Metabolism

Antioxidants & Redox Signaling, 2017
Cellular metabolic activity impacts the production of reactive oxygen species (ROS), both positively through mitochondrial oxidative processes and negatively by promoting the production of reducing agents (including NADPH and reduced glutathione). A defined metabolic state in cancer cells is critical for cell growth and long-term self-renewal, and such
Sarah Tessier, N. Martín-Martín, H. de Thé, A. Carracedo, V. Lallemand-Breitenbach   +4 more
semanticscholar   +4 more sources