Results 191 to 200 of about 43,079 (212)

[Research advances on function of promyelocytic leukemia (PML) protein].

Ai zheng = Aizheng = Chinese journal of cancer, 2004
Through reviewing research advances on promyelocytic leukemia(PML) protein at home and abroad in recent years, the authors summarized the biological functions of PML protein in this paper. Recent researches indicated that all PML protein isoforms have RBCC (Ring finger domain, B-box, Coiled-Coil domain, RBCC)or TRIM (TRIpartite motif).
Peng-Cheng, He, Mei, Zhang, Fang, Wang
openaire   +1 more source

Interplay of protein misfolding pathway and unfolded-protein response in acute promyelocytic leukemia

Expert Review of Proteomics, 2010
Protein misfolding has traditionally been linked to the pathogenesis of various neurodegenerative diseases. However, emerging evidence from various laboratories, including ours, suggests that protein misfolding may also play a fundamental role in some malignancies, particularly those caused by fusion oncoprotein generated from chromosomal translocation.
openaire   +2 more sources

The PML-RARα Fusion Protein and Targeted Therapy for Acute Promyelocytic Leukemia

Leukemia & Lymphoma, 2004
Acute promyelocytic leukemia (APL) is an unique subtype of acute myeloid leukemia typically carrying a specific reciprocal chromosome translocation t(15;17) leading to the expression of a leukemia-generating fusion protein, PML-RARalpha. Nearly all de novo APL patients undergo disease remission when treated with all trans retinoic acid (ATRA) plus ...
openaire   +2 more sources

The RING domain of human promyelocytic leukemia protein (PML)

Journal of Biomolecular NMR, 2015
Shu-Yu, Huang, Chi-Fon, Chang, Pei-Ju, Fang, Mandar T, Naik, Peter, Güntert, Hsiu-Ming, Shih, Tai-Huang, Huang   +6 more
openaire   +2 more sources

The B-box 1 dimer of human promyelocytic leukemia protein

Journal of Biomolecular NMR, 2014
Shu-Yu, Huang, Mandar T, Naik, Chi-Fon, Chang, Pei-Ju, Fang, Ying-Hui, Wang, Hsiu-Ming, Shih, Tai-Huang, Huang   +6 more
openaire   +2 more sources

The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

Cell, 1993
Francesco Grignani, Pier Francesco Ferrucci, Ugo Testa   +2 more
exaly  

Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia

New England Journal of Medicine, 2013
Giuseppe Avvisati, Marco Vignetti, Christian Thiede   +2 more
exaly  

Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)

New England Journal of Medicine, 1991
Michael Andreeff, Agostino Tafuri
exaly  

Complete Remission after Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide

New England Journal of Medicine, 1998
Peter G Maslak, Pier Paolo Pandolfi
exaly  

Resistance to Therapy in Acute Promyelocytic Leukemia

New England Journal of Medicine, 2014
Jacqueline Lehmann-Che, Hugues de The
exaly