Comparison of changes in blood cells and hemostatic biomarkers in mouse xenograft models of acute myeloid leukemia and acute promyelocytic leukemia. [PDF]
Archibald SJ +5 more
europepmc +1 more source
Pro-Apoptotic and Cytotoxic Effects of Melittin on HL-60 Acute Promyelocytic Leukemia Cells: Implications for Retinoid-Independent Therapy. [PDF]
Stela M +6 more
europepmc +1 more source
Acute Promyelocytic Leukemia Presenting as Spontaneous Abortion Amidst Tropical Fever Season: A Diagnostic Challenge. [PDF]
Rathod A, Gupta M, Palta A.
europepmc +1 more source
Severe Gout During Arsenic Therapy: Insights on Oxidative Stress and Interleukin-1β in Gout. [PDF]
Hamilton J, Alexander A.
europepmc +1 more source
JC Virus Agnogene Regulates Histone-Modifying Enzymes via PML-NBs: Transcriptomics in VLP-Expressing Cells. [PDF]
Shishido-Hara Y, Yaoi T.
europepmc +1 more source
Association between leukemic immunophenotype and overall survival in patients with acute promyelocytic leukemia: a retrospective cohort study. [PDF]
Zha X +5 more
europepmc +1 more source
Related searches:
Acute promyelocytic leukemia (APL) is driven by the promyelocytic leukemia (PML)-retinoic acid receptor-α (PML-RARA) fusion protein, which interferes with nuclear receptor signaling and PML nuclear body (NB) assembly. APL is the only malignancy definitively cured by targeted therapies: retinoic acid (RA) and/or arsenic trioxide, which both trigger PML ...
Julien Ablain +5 more
openaire +4 more sources
Promyelocytic leukemia protein: an atherosclerosis suppressor protein?
Clinical Science, 2021Abstract As many as 70% of cells in atherosclerotic plaque are vascular smooth muscle cell (VSMC) in origin, and pathways and proteins which regulate VSMC migration, proliferation, and phenotype modulation represent novel targets for rational drug design to reduce atherosclerotic vascular disease.
Cali B, Corbett +2 more
openaire +2 more sources
AbstractAcute promyelocytic leukemia (APL) is a hematological emergency in which a rapid diagnosis is essential for early administration of appropriate therapy, including all‐trans retinoic acid before the onset of fatal coagulopathy. Currently, the following methodologies are widely used for rapid initial diagnosis of APL: 1) identification of ...
Mirabelli P. +10 more
openaire +3 more sources

