Results 61 to 70 of about 10,218 (198)

Rate-dependency of action potential duration and refractoriness in isolated myocytes from the rabbit AV node and atrium [PDF]

, 2000
During atrial fibrillation, ventricular rate is determined by atrioventricular nodal (AVN) conduction, which in part is dependent upon the refractoriness of single AVN cells.
Andrew C. Rankin, Antony J. Workman, Anyukhovsky, Billette, Boyett, Cagin, Carmeliet, Dawodu, Delmar, Delmar, Denes, Duan, Fermini, Ferrier, Gibbs, Giles, Giles, Green, Hancox, Hoshino, Howarth, Isenberg, Jurkiewicz, Kaab, Kathleen A. Kane, Kukushkin, Li, Li, Meijler, Meijler, Mitcheson, Munk, Nakayama, Nattel, Nayebpour, Neher, Nilius, Petrecca, Rankin, Ravens, Shibata, Shigematsu, Tanaka, Vaughan-Williams, Wang, Wang, Wang, Wenckebach, Workman   +48 more
core   +1 more source

Genetic insights into congenital heart disease: Prevalence, aetiology and clinical implications

Clinical and Translational Discovery, Volume 5, Issue 5, October 2025.
The review synthesizes current knowledge on the genetic underpinnings of congenital heart disease, highlighting how modern genomic technologies enhance understanding of CHD pathogenesis and enable earlier diagnosis. We demonstrate how these genetic insights translate to improved clinical care, risk assessment, and genetic counseling for affected ...
Yuan Yuan, Yi Jia, Shasha Peng, Shuru Zhao, Kang Dong, Yuruo Hu, Zicheng Zhao, Xiaofei Jiang, Zhe Zhang   +8 more
wiley   +1 more source

POSSIBLE PREDICTORS OF ATRIAL FIBRILLATION RECURRENCE IN LONG-TERM PROPHYLACTIC PROPAFENONE THERAPY

Рациональная фармакотерапия в кардиологии, 2015
Aim. To identify possible predictors of atrial fibrillation (AF) recurrence in 6-month prophylactic propafenone therapy. Material and methods. Patients (n=63; aged 52.2±12.6 years; 25.4% women) with frequent AF recurrences who restored sinus rhythm with ...
R. D. Kurbanov, N. U. Zakirov, Sh. K. Azizov, Kh. M. Raubzhanov   +3 more
doaj   +3 more sources

Propafenone in restoring sinus rhythm among patients with persistent atrial fibrillation. PROMETEY – an open, multicenter, pilot study performed in the Russian Federation (part II)

Кардиоваскулярная терапия и профилактика, 2005
Aim. To study efficacy and safety of propafenone (450 mg/d per os) in maintaining sinus rhythm among patients with persistent atrial fibrillation (AF). Material and methods.
I. G. Fomina, A. I. Tarzimanova, A. V. Vetluzhsky, A. A. Abramova   +3 more
doaj  

Endothelial function changes in paroxysmal atrial fibrillation and treatment with propafenone

Кардиоваскулярная терапия и профилактика, 2018
Aim. To evaluate the changes of endothelial function in arterial hypertension (AH) patients with paroxysmal atrial fibrillation (AF) in treatment with propafenone (Propanorm, PRO.MED.CS Praha a. s.) in comparison with bisoprolol.Material and methods.
V. I. Podzolkov, A. I. Tarzimanova
doaj   +1 more source

Development of an Artificial Intelligence Powered Medication Risk Score Calculator Application

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 4, October 2025.
ABSTRACT The publication explores the development of the Augmented Medication Risk Score (AUGMERIS) calculator, a web application supported by artificial intelligence, designed to automate the evaluation of medication therapies with the Danish Medication Risk Score (MERIS) method.
Ádám Bertalan, Viola Angyal, Péter Domján, Eva Aggerholm Sædder, Gyula Király, Lóránd Erdélyi, Nóra Gyimesi, Elek Dinya   +7 more
wiley   +1 more source

Short- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation* [PDF]

, 2006
Introduction: Segmental ostial pulmonary vein isolation (PVI) is considered a potentially curative therapeutic approach in the treatment of paroxysmal atrial fibrillation (PAF).
Aichinger, J, Janssen, J, Martinek, M, Nesser, H.J, Pürerfellner, H   +4 more
core   +1 more source

Medical treatment of cardiac arrhythmias in Chagas'heart disease [PDF]

, 1995
There are no controlled clinical trials evaluating drug therapy in patients with ventricular arrhythmias and chronic chagasic cardiomyopathy. Empirical treatment with disopyramide (400-1,000mg/d), phenytoin (4-6mg/d), mexiletine (600-1,200mg/d ...
De Paola, Angelo Amato Vincenzo, Gondin, Fernando Antonio Aquino, Hara, Vanderlei, Mendonça, Alayde   +3 more
core   +1 more source

Effect of Propafenone on the Contractile Activity of Latissimus Dorsi Muscle Isolated in an Organ Chamber: Experimental Study in Rats

Arquivos Brasileiros de Cardiologia, 2002
OBJECTIVE: To study the effect of propafenone on the contractile function of latissimus dorsi muscle isolated from rats in an organ chamber. METHODS: We studied 20 latissimus dorsi muscles of Wistar rats and divided them into 2 groups: group I (n=10), or
Ricardo Simões, Eduardo Luis Guimarães Machado, Odilon Gariglio de Alvarenga Freitas, Maria da Consolação Vieira Moreira, Otoni Moreira Gomes   +4 more
doaj   +1 more source

Defining the polycystin pharmacophore through high‐throughput screening and computational biophysics

British Journal of Pharmacology, Volume 182, Issue 19, Page 4611-4624, October 2025.
An unbiased high throughput electrophysiology screen identifies potent PKD2L1 channel inhibitors with divergent chemical composition that bind to pore fenestration receptors and stabilise their inactivated state. Abstract Background and Purpose Polycystins (PKD2, PKD2L1) are voltage‐gated and Ca2+‐modulated members of the TRP family of ion channels ...
Eduardo Guadarrama, Carlos G. Vanoye, Paul G. DeCaen   +2 more
wiley   +1 more source