Results 131 to 140 of about 1,668 (193)

Enteroids to Study Pediatric Intestinal Drug Transport. [PDF]

Mol Pharm
Streekstra EJ, Keuper-Navis M, van den Heuvel JJMW, van den Broek P, Stommel MWJ, de Boode W, Botden S, Bervoets S, O'Gorman L, Greupink R, Russel FGM, van de Steeg E, de Wildt SN.   +12 more
europepmc   +1 more source

Early Intravenous Beta-Blockade with Esmolol in Adults with Severe Traumatic Brain Injury (EBB-TBI): Protocol for a Phase 2a Intervention Design Study. [PDF]

Neurocrit Care
Thomas M, Hayes K, White P, Ramesh A, Culliford L, Ackland G, Pickering A.   +6 more
europepmc   +1 more source

In Vitro Characterization of Ephedrine-Related Stereoisomers at Biogenic Amine Transporters and the Receptorome Reveals Selective Actions as Norepinephrine Transporter Substrates [PDF]

Beth A. Compton-Toth, Bryan L. Roth, John S. Partilla, Jon Birkes, Nga Vu, Richard A. Glennon, Richard B. Rothman, Richard Young, Sandra J. Hufeisen   +8 more
core   +1 more source

Effects of carvedilol on human prostate tissue contractility and stromal cell growth pointing to potential clinical implications. [PDF]

Pharmacol Rep
Hu S, Müderrisoglu AE, Ciotkowska A, Kale O, Keller P, Schott M, Tamalunas A, Waidelich R, Stief CG, Hennenberg M.   +9 more
europepmc   +1 more source

Metabolomics of repetitive myocardial stunning in chronic multivessel coronary artery stenosis: Effect of non-selective and selective β1-receptor blockers. [PDF]

J Physiol
Le DE, Alkayed NJ, Cao Z, Chattergoon NN, Garcia-Jaramillo M, Thornburg K, Kaul S.   +6 more
europepmc   +1 more source

Bento: a toolkit for subcellular analysis of spatial transcriptomics data. [PDF]

Genome Biol
Mah CK, Ahmed N, Lopez NA, Lam DC, Pong A, Monell A, Kern C, Han Y, Prasad G, Cesnik AJ, Lundberg E, Zhu Q, Carter H, Yeo GW.   +13 more
europepmc   +1 more source

Carrier cross-reactivities of the bile acid reabsorption inhibitors elobixibat, linerixibat, maralixibat, and odevixibat. [PDF]

J Lipid Res
Billo V, Neelen C, Wannowius M, Neubauer A, Fühler B, Hagos Y, Geyer J.   +6 more
europepmc   +1 more source

Orphan Three-Finger Toxins from Snake Venoms: Unexplored Library of Novel Biological Ligands with Potential New Structures and Functions. [PDF]

Int J Mol Sci
Koh CY, Kini RM.
europepmc   +1 more source

2D QSAR of heteroaryl-substituted propanolamines as antihypertensive agents

Medicinal Chemistry Research, 2013
Propanolamines are well known for their ability to reduce blood pressure. A number of propanolamines have been approved as antihypertensive agents. A series of propanolamines was selected and different models based on multiple linear regression (MLR) were generated to find out correlation between the physicochemical parameters and the biological ...
Prasanna A. Datar, M. H. Washimkar
openalex   +2 more sources

Synthesis of propanolamine side chain deuterated propranolol, propranolol‐diol and 4‐hydroxypropranol

Journal of Labelled Compounds and Radiopharmaceuticals, 1978
AbstractSyntheses of 1‐(isopropylamino)‐3‐(1‐naphthyloxy)‐2‐propanol‐1,1,2,3,3‐d5 (1), 3‐(1‐naphthyloxy)‐1,2‐propanediol‐1,1,2,3,3‐d5 (2) and 1‐(isopropylamino)‐3‐(4‐hydroxy‐1‐naphthyloxy)‐2‐propanol‐1,1,2,3,3‐d5 (3) from epichlorohydrin‐d5 are described. Treatment of epichlorohydrin‐d5 with 1‐naphthol, in the presence of a catalytic amount of pyridine,
Richard B. Walker, Wendel L. Nelson
openalex   +2 more sources