Results 141 to 150 of about 1,962 (207)
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Beta-Adrenergic blocking agents. Nitrogen heteroaryl-substituted 2-propanolamines and ethanolamines.

Journal of Medicinal Chemistry, 1973
AbstractEine Reihe von Methylheterocyclen (I) wird in Form ihrer Lithiumderivate (II) mit den Aminoacetonitrilen (III) zu den Enaminen (IV) umgesetzt, die durch Hydrolyse, Reduktion mit Natriumborhydrid und hydrierende Debenzylierung in Propanolamine (VII) umgewandelt werden.
R. F. Meyer   +3 more
semanticscholar   +5 more sources

Persistence and Biodegradation of Monoethanolamine and 2-Propanolamine at an Abandoned Industrial Site

open access: closedEnvironmental Science & Technology, 2005
Soil and groundwater samples were collected at the site of a former chemical processing plant in areas impacted by accidental releases of MEA (monoethanolamine) and IPA (2-propanolamine or isopropanolamine). Although their use had ceased ca. 10 years before sample collection, soils collected at contamination sites had MEA concentrations ranging from ca.
Steven B. Hawthorne   +4 more
openalex   +4 more sources

3-(Acyloxy)propanolamines : agents with β-adrenergic blocking activity

European Journal of Medicinal Chemistry, 1994
Abstract A series of totally aliphatic 3-(acyloxy)propanolamine derivatives were prepared and their pA2-values were determined employing the guinea-pig atrium. Compounds with an acetyl or methyl succinoyl half ester moiety showed a pronounced β1-adrenergic blocking activity.
J. Leuschner, H. Schäfer, F. Leuschner
semanticscholar   +3 more sources

o-Allyloxy-phenoxy-propanolamine, eine neue Gruppe adrenergischer β-Rezeptoren-Blocker

open access: closedExperientia, 1967
The synthesis of a new class of adrenergicβ-receptor blocking agents based upon ao-allyloxy-phenoxy-propanolamine structure is described. The structure activity relationships were studied, and the structural elements responsible for an optimal pharmacological effect are discussed.
M. Wilhelm, P. R. Hedwall, Max Meier
openalex   +4 more sources

ChemInform Abstract: SYNTHESIS AND ADRENERGIC β-BLOCKING ACTIVITY OF SOME PROPANOLAMINE DERIVATIVES

open access: closedChemischer Informationsdienst, 1978
AbstractEs werden einige Propanolamin‐Derivate wie z.B. (I) und (II) dargestellt, von denen erstere bessere β‐Blocker als Sotalol sind.
H. OBASE   +7 more
openalex   +3 more sources

A new series of tricyclic (aryloximino)propanolamines displaying very high selective .beta.2-blocking properties

Journal of Medicinal Chemistry, 1989
A new class of indanones 4 easily obtained by aryne type condensations, followed by transposition of the benzocyclobutanols 3 thus formed, were transformed into the corresponding oximinopropanolamines 7.
B. Jamart-Grégoire   +4 more
semanticscholar   +4 more sources

Crystal structure and magnetic properties of a Cu4O4 cubane complex with N-(2-hydroxybenzyl)-propanolamine

open access: closedInorganic Chemistry Communications, 2001
Abstract The crystal structure of [ Cu ( L 1 )] 4 ( 1 ) (H2L1=N-(2-hydroxybenzyl)-propanolamine) contains a Cu4O4 cubane core, involving four intramolecular hydrogen bonds. Magnetic studies reveal a good linear correlation between 2J and the bridge angle φ; the more antiferromagnetic trend than the literature correlations for ...
Yongshu Xie   +6 more
openalex   +3 more sources

A first-principle study of CO2 binding by monoethanolamine and mono-n-propanolamine solutions

open access: closedChemical Physics, 2015
Abstract Monoethanolamine (MEA) and mono- n -propanolamine (MPA) molecules were investigated for CO 2 binding using Density Functional Theory. MPA was predicted to bind CO 2 better than MEA along the bimolecular and trimolecular pathways. The additional CH 2 in MPA provided additional polarization to reduce the electrostatic repulsion for the ...
Hsueh-Chien Li, Ming‐Kang Tsai
openalex   +3 more sources

ChemInform Abstract: SYNTHESIS OF A NOVEL SERIES OF (ARYLOXY)PROPANOLAMINES: NEW SELECTIVE β2‐BLOCKING AGENTS

open access: closedJournal of Medicinal Chemistry, 1984
AbstractDurch Cycloaddition der den Verbindungen (I) entsprechenden Arine mit den Enolaten (II) erhält man die Schlüsselverbindungen (III) und (IV), die über die Phenole (V) in die Phenolether (VI) umgewandelt werden.
M. C. Carré   +5 more
openalex   +5 more sources

Complex Compounds with Amino Alcohols. Part 1. Complexes Containing Propanolamines as Ligands

ChemInform, 1994
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. Brezeanu   +3 more
semanticscholar   +3 more sources

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