Results 31 to 40 of about 29,135 (265)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Star Proper Motions Based on Two-epoch Observations from the SDSS and DESI Imaging Surveys
The Astronomical JournalIn this study, we present the construction of a new proper-motion catalog utilizing the photometric data from the Sloan Digital Sky Survey (SDSS) and Dark Energy Spectroscopic Instrument (DESI) imaging surveys, with a median time baseline of about 13 yr.
Yun-Ao Xiao +11 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The Astrophysical JournalIt is commonly supposed that quenched field dwarfs near the edge of the Local Group (LG) are backsplash galaxies, having previously orbited within the Milky Way (MW) or M31’s virial radius, whereas galaxies on first infall should still have gas and star ...
Paul Bennet +10 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The Astrophysical JournalWe have determined the proper motions (PMs) of 12 dwarf galaxies in the Local Group (LG), ranging from the outer Milky Way (MW) halo to the edge of the LG.
Paul Bennet +14 more
doaj +1 more source
, 2013 Proper Motion (in the sense of "intrinsic to the object") is the apparent angular motion of stars across the sky, due to their orbits around the center of the Milky Way Galaxy. Lacking any depth perception, astronomers have to use different techniques to measure a star’s radial (directly toward or away from us) and transverse (across the sky) motions ...
openaire +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
SMDET-1: A Nearby Y-dwarf Candidate
The Astronomical JournalWe present the discovery of SMDET-1, a red, fast-moving object ( $\mu \approx 1\mathop{.}\limits{^{\prime\prime} }3$ yr ^−1 ) identified in time-resolved unblurred Wide-field Infrared Survey Explorer coadds using a pixel-level deep learning methodology ...
Aaron M. Meisner +14 more
doaj +1 more source