Results 41 to 50 of about 1,114,768 (299)

Star Proper Motions Based on Two-epoch Observations from the SDSS and DESI Imaging Surveys

open access: yesThe Astronomical Journal
In this study, we present the construction of a new proper-motion catalog utilizing the photometric data from the Sloan Digital Sky Survey (SDSS) and Dark Energy Spectroscopic Instrument (DESI) imaging surveys, with a median time baseline of about 13 yr.
Yun-Ao Xiao   +11 more
doaj   +1 more source

3D simulation of laminated shell structures using the Proper Generalized Decomposition [PDF]

open access: yes, 2014
Numerical simulations of composite structures are generally performed using multi-layered shell elements in the context of the finite elements method. This strategy has numerous advantages like a low computation time and the capability to reproduce the ...
PRULIERE, Etienne
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Orbits of Isolated Dwarfs in the Local Group from New 3D Kinematics: Constraints on First Infall, Backsplash, and Quenching Mechanisms

open access: yesThe Astrophysical Journal
It is commonly supposed that quenched field dwarfs near the edge of the Local Group (LG) are backsplash galaxies, having previously orbited within the Milky Way (MW) or M31’s virial radius, whereas galaxies on first infall should still have gas and star ...
Paul Bennet   +10 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

SMDET-1: A Nearby Y-dwarf Candidate

open access: yesThe Astronomical Journal
We present the discovery of SMDET-1, a red, fast-moving object ( $\mu \approx 1\mathop{.}\limits{^{\prime\prime} }3$ yr ^−1 ) identified in time-resolved unblurred Wide-field Infrared Survey Explorer coadds using a pixel-level deep learning methodology ...
Aaron M. Meisner   +14 more
doaj   +1 more source

A GLOBAL CORRECTION TO PPMXL PROPER MOTIONS

open access: yes, 2016
In this paper we note that extragalactic sources seem to have non-zero proper motions in the PPMXL proper motion catalog. We collect a large, all sky sample of extragalactic objects and fit their reported PPMXL proper motions to an ensemble of spherical ...
Roeser, Siegfried   +2 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Proper Motions and Orbits of Distant Local Group Dwarf Galaxies from a Combination of Gaia and Hubble Data

open access: yesThe Astrophysical Journal
We have determined the proper motions (PMs) of 12 dwarf galaxies in the Local Group (LG), ranging from the outer Milky Way (MW) halo to the edge of the LG.
Paul Bennet   +14 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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