Results 41 to 50 of about 29,135 (265)
The Astrophysical Journal, 2023 We present proper motion measurements of the oxygen-rich ejecta of the LMC supernova remnant N132D using two epochs of Hubble Space Telescope Advanced Camera for Surveys data spanning 16 years.
John Banovetz +10 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Verification of Hypervelocity Bulge Red Clump Stars
The Astronomical JournalWe verify candidate hypervelocity red clump stars located in the Galactic bulge that were selected based on the VVV and the Gaia DR2 data by Luna et al. To do so, we analyze data from the OGLE-IV survey: difference images and astrometric time series.
Gabriela Wojtkowska, Radosław Poleski
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
IRS 9: The Case for a Dynamically Ejected Star from the Galactic Center
The Astrophysical Journal LettersMeasuring stellar motions at the Milky Way’s Galactic center (GC) provides unique insight into the dynamical processes within galactic nuclei. We present proper-motion measurements for 23 SiO-maser-emitting stars within 45″ of SgrA*, including four ...
Matthew W. Hosek Jr. +9 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Astrometric star catalogues as combination of Hipparcos/Tycho catalogues with ground-based observations [PDF]
Serbian Astronomical Journal, 2004 The successful ESA mission Hipparcos provided very precise parallaxes positions and proper motions of many stars in optical wavelength. Therefore it is a primary representation of International Celestial Reference System in this wavelength.
Vondrák J.
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source