Results 161 to 170 of about 177,045 (348)

Influence of 2(3-Methyl-cinnamyl-hydrazono)-propionate on Glucose and Palmitate Oxidation in Human Mononuclear Leukocytes. Hydrazonopropionic Acids, a New Class of Hypoglycaemic Substances, VII

, 1987
Rainer Haeckel, Patrick Fink, Michael Oellerich   +2 more
openalex   +2 more sources

Impact of dietary propionate on fructose-induced changes in lipid metabolism, gut microbiota and short-chain fatty acids in mice

, 2020
Christine Brütting, Milena Lara Bisch, Corinna Brandsch, Frank Hirche, Gabriele I. Stangl   +4 more
openalex   +2 more sources

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

ChemistryOpen, EarlyView.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda, Sami A. Al‐Hussain, Basant Farag, Mohamed El‐Naggar, Magdi E. A. Zaki, Emad S. A. Alhazmi, Adel S. M. Almohammadi, Sobhi M. Gomha   +7 more
wiley   +1 more source

A Swollen Finger and a Silent Rash

JEADV Clinical Practice, EarlyView.
Takuya Mizukami, Joohyung Youh, Kazusa Hyodoh, Kei Ito   +3 more
wiley   +1 more source

Rieske Iron–Sulfur Cluster Proteins From an Anaerobic Ammonium Oxidizer Suggest Unusual Energetics in Their Parent Rieske/Cytochrome b Complexes

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Anaerobic ammonium‐oxidizing (anammox) bacteria employ a unique, hydrazine‐based pathway to obtain energy from nitrite and ammonium. These organisms possess distinct Rieske/cytochrome b complexes whose precise role in anammox metabolism remains unclear, but which have been proposed to include the generation of NAD(P)H.
David Hauser, Mandy Sode, Elena A. Andreeva, Kristian Parey, Thomas R. M. Barends   +4 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionate Receptor Subunit Composition and cAMP-response Element-binding Protein Regulate Oligodendrocyte Excitotoxicity

, 2006
Wenbin Deng, Rachael L. Neve, Paul A. Rosenberg, Joseph J. Volpe, Frances E. Jensen   +4 more
openalex   +1 more source

Baicalin Restores the Hypoglycemic Effect of Metformin by Regulating the Microbial Imidazole Propionate and Short‐Chain Fatty Acids

Phytotherapy Research, EarlyView.
Baicalin restores the hypoglycemic effect of metformin by decreasing the serum imidazole propionate. ABSTRACT Gut microbiota dysbiosis is implicated in metformin non‐response. This study aimed to investigate whether baicalin, a microbiota‐modulating flavonoid derived from Radix Scutellariae, could restore metformin sensitivity and explored the ...
Aiting Wang, Zenghui Miao, Bangrong Huang, Jiayu Zeng, Mingxia Yuan, Dan Yan   +5 more
wiley   +1 more source

Distribution of the methylcitric acid cycle and .BETA.-oxidation pathway for propionate catabolism in fungi.

, 1987
Shunichi Miyakoshi, Hiroo Uchiyama, Takashi Someya, Takayori Satoh, Takeshi Tabuchi   +4 more
openalex   +2 more sources

Bioavailability and disposition of azelastine and fluticasone propionate when delivered by MP29‐02, a novel aqueous nasal spray [PDF]

, 2012
Hartmut Derendorf, Ullrich Munzel, U. Petzold, Joachim Maus, Hermann Mascher, Róbert Hermann, Jean Bousquet   +6 more
openalex   +1 more source