Results 211 to 220 of about 133,034 (264)

In Vitro Performance of Valved Holding Chambers in Paediatric Asthma Controller Therapy

Acta Paediatrica, EarlyView.
ABSTRACT Aim Research on the drug delivery of inhaled corticosteroids and combination medications via valved holding chambers (VHCs) with children's breathing patterns is limited. We aimed to evaluate the in vitro performance of commercially available VHCs without facemasks under preschooler breathing conditions, focusing on total delivered dose and ...
Laura Ojanperä, Lauri Lehtimäki, Péter Csonka   +2 more
wiley   +1 more source

Efficacy and safety of clobetasol propionate ophthalmic nanoemulsion for treating intraocular inflammation and pain associated with cataract surgery: two phase 3 multicentre, randomised, placebo-controlled, double-masked clinical studies. [PDF]

BMJ Open
Schwartz A, Wellish K, Zaman F, Jong K, Sadri E, Martel J, Peace J, Korenfeld M.   +7 more
europepmc   +1 more source

Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy

Alimentary Pharmacology &Therapeutics, EarlyView.
The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins, Srinivas Kamath, Rachel H. Davis, Samuel P. Costello, Robert V. Bryant, Alice S. Day, Paul Joyce   +6 more
wiley   +1 more source

Free fatty acid receptor 2 allosterism is defined by cellular context. [PDF]

Cell Commun Signal
Lind S, Abdi Ali A, Al Hamoud Al Asswad S, Lauschke VM, Forsman H, Dahlgren C, Johansson LC.   +6 more
europepmc   +1 more source

Temperature-driven shifts in microbial reactions and community structure in bentonite under Fe(III)- and sulfate-reducing conditions: implications for deep geological repository performance. [PDF]

Appl Environ Microbiol
Park K, Zhang Y, Jang YS, Lee S-H, Kwon J-S, Im J, Kwon MJ.   +6 more
europepmc   +1 more source

Assessment of Components Associated with Average Daily Gain of Finishing Lambs Fed with Two Roughage Sources Using Integrative Metabolomics. [PDF]

Animals (Basel)
Ma J, Wang S, Yang D, Chen X, Tu Y, Ma T.   +5 more
europepmc   +1 more source

Malic Acid Supplementation on Rumen Fermentation, Nutrient Digestibility, Performance and Carcass Traits in Lambs: A Meta-Analysis and Meta-Regression Considering Dietary Moderators. [PDF]

Animals (Basel)
Rocha LTD, Skonieski F, Del Valle TA, Facco FB, Selau PO, Oliveira KP, Zucheto AV, Viégas J.   +7 more
europepmc   +1 more source

Propionate metabolism is dysregulated in non-small cell lung cancer patients and EGFR-mutant drug-tolerant persister cells. [PDF]

Sci Rep
Parang B, Yoffe L, Khan R, Li Z, Nagiec MJ, Gardner EE, Shieh Y, Heise RS, Saxena A, Altorki N, Blenis J.   +10 more
europepmc   +1 more source

Cold-Induced Serum Short-Chain Fatty Acids Act as Markers of Brown Adipose Tissue Metabolism in Humans.

J Clin Endocrinol Metab
Monfort-Pires M, U-Din M, de Mello V, Saari T, Raiko J, Kerminen E, Rajander J, Hanhineva K, Fromme T, Landberg R, Klingenspor M, Virtanen KA.   +11 more
europepmc   +1 more source