Results 81 to 90 of about 192,124 (377)

Healthy effects of prebiotics and their metabolites against intestinal diseases and colorectal cancer

open access: yesAIMS Microbiology, 2015
A specific group of plant and animal oligosaccharides does not suffer enzymatic digestion in the human upper intestinal tract, achieving the colon microbial ecosystem in intact form.
Javier Fernández   +5 more
doaj   +1 more source

Enhancing Mechanical Deformability of Rigid Conjugated Polymers through Functional Additive‐Induced Persistence Length Modulation

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates a molecular strategy to enhance the stretchability of conjugated polymers by incorporating plasticizing molecular additives (PMAs). PMAs reduce the persistence length and promote chain entanglement, enabling deformable thin films with preserved electrical performance. A systematic analysis combining rheology, neutron scattering,
Sein Chung   +11 more
wiley   +1 more source

Short-term memory trace mediated by termination kinetics of olfactory receptor. [PDF]

open access: yes, 2016
Odorants activate receptors in the peripheral olfactory neurons, which sends information to higher brain centers where behavioral valence is determined.
Boyle, Sean Michael   +3 more
core   +1 more source

Stiffening Liquid Crystal Elastomers with Liquid Crystal Inclusions

open access: yesAdvanced Materials, EarlyView.
Incorporation of low molecular weight liquid crystals (LC) into liquid crystal elastomers (LCE) leads to a significant increase in their stiffness and output work density. Such remarkable stiffening is attributed to nanoscale phase‐separation and the formation of induced‐smectic domains in polydomain and monodomain LC‐LCEs, respectively.
Sahad Vasanji   +7 more
wiley   +1 more source

Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD [PDF]

open access: yes, 2015
Objective We performed a review of studies of fluticasone propionate (FP)/salmeterol (SAL) (combination inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA)) in patients with COPD, which measured baseline (pretreatment) blood eosinophil levels, to ...
Barnes, NC   +6 more
core   +1 more source

Quantification of Propionate

open access: yesThe FASEB Journal, 2018
The metabolism of propionate, a 3‐carbon short chain fatty acid, via propionyl‐CoA to 2‐methyl‐2‐pentenoic acid (2M2PE), a 6‐carbon intermediate, was recently and unexpectedly reported to occur in humans. The enzymology and further metabolism of this pathway remains unclear, but investigations into the metabolism of 2M2PE are an untested avenue in ...
Jimmy P. Xu   +4 more
openaire   +1 more source

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz   +14 more
wiley   +1 more source

The ratios of dietary non-fibrous carbohydrate (NFC) to neutral detergent fiber (NDF) influence intestinal immunity of rabbits by regulating gut microbiota composition and metabolites

open access: yesFrontiers in Microbiology, 2023
Carbohydrate is the most common macronutrient consumed across all phases of the diet and acts as a potential regulator in modulating the gut microbiota in animals.
Shuo Li   +12 more
doaj   +1 more source

Defining Resonance Raman Spectral Responses to Substrate Binding by Cytochrome P450 from \u3cem\u3ePseudomonas putida\u3c/em\u3e [PDF]

open access: yes, 2008
Resonance Raman spectra are reported for substrate-free and camphor-bound cytochrome P450cam and its isotopically labeled analogues that have been reconstituted with protoheme derivatives that bear -CD3 groups at the 1, 3, 5, and 8-positions (d12 ...
Deng, Tianjing   +5 more
core   +1 more source

Inhaled corticosteroids versus long-acting beta -agonists for chronic obstructive pulmonary disease (Review). [PDF]

open access: yes, 2011
Long-acting beta(2)-agonists and inhaled corticosteroids can be used as maintenance therapy by patients with moderate to severe chronic obstructive pulmonary disease. These interventions are often taken together in a combination inhaler.
Agarwal   +105 more
core   +2 more sources

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