Results 91 to 100 of about 152,792 (340)

In‐hospital outcomes of lacosamide versus levetiracetam for early adjunctive treatment of status epilepticus: A Nationwide Japanese retrospective cohort study

Epilepsia Open, EarlyView.
Abstract Objective Status epilepticus (SE) is a neurological emergency requiring immediate treatment. Although intravenous lacosamide (LCM) is used for the management of epilepsy, its effectiveness in treating SE remains unclear. We aimed to compare the in‐hospital outcomes between intravenous LCM and levetiracetam (LEV) as an early adjunctive therapy ...
Yumiko Nakamura, Shotaro Aso, Hideo Yasunaga, Hiroki Matsui, Yuichiro Shirota, Masashi Hamada, Kiyohide Fushimi, Tatsushi Toda, Satoshi Kodama   +8 more
wiley   +1 more source

Propofol enhances BCR-ABL TKIs’ inhibitory effects in chronic myeloid leukemia through Akt/mTOR suppression

BMC Anesthesiology, 2017
Background The anti-cancer activities of intravenous anesthetic drug propofol have been demonstrated in various types of cancers but not in chronic myeloid leukemia (CML). Methods We systematically examined the effect of propofol and its combination with
Zhimin Tan, Aixia Peng, Jingwen Xu, Mingwen Ouyang   +3 more
doaj   +1 more source

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

Ibrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Effects of propofol-based total intravenous anesthesia on recurrence and overall survival in patients after modified radical mastectomy: a retrospective study

Korean Journal of Anesthesiology, 2016
Background The optimal combination of anesthetic agent and technique may have an influence on long-term outcomes in cancer surgery. In vitro and in vivo studies suggest that propofol independently reduces migration of cancer cells and metastasis.
Ji Heui Lee, S. Kang, Yunkwang Kim, H. A. Kim, Bongseog Kim   +4 more
semanticscholar   +1 more source

External cephalic version outcomes with tocolysis and sedation: A 10‐year retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the effectiveness and safety of external cephalic version (ECV) performed with tocolysis and sedation or spinal anesthesia, and to identify predictors of ECV success, complications, and delivery outcomes after successful ECV. Methods This 10‐year cohort study included 990 pregnant women with term non‐cephalic presentation
Javier Sánchez‐Romero, Rosa María Gallego‐Pozuelo, José Eliseo Blanco‐Carnero, Javier Herrera‐Giménez, Fernando Araico‐Rodríguez, Alberto Rafael Guijarro‐Campillo, Aníbal Nieto‐Díaz, Catalina de Paco‐Matallana   +7 more
wiley   +1 more source

Comparison of serum triglyceride levels with propofol in long chain triglyceride and propofol in medium and long chain triglyceride after short term anesthesia in pediatric patients

Saudi Journal of Anaesthesia, 2014
Background: Significant increase in serum triglyceride (ST) concentration have been described in adult population after prolonged administration of propofol formulation containing long chain triglyceride (LCT).
Ishwar Bhukal, Gokul Thimmarayan, Indu Bala, Sohan Lal Solanki, Tanvir Samra   +4 more
doaj   +1 more source

Safety of MRI Examinations Under Sedation: A Nationwide Survey in Japan

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MRI is performed under sedation for patients requiring immobility or for those already sedated for clinical management. Although specialist guidelines advocate for anesthesiologist‐led care, non‐anesthesiologist‐led adult sedation is a common practice worldwide. Furthermore, the increase in risk attributable to sedation has not been
Shiori Amemiya, Masako Kataoka, Tsukasa Doi, Toshinori Hirai, Takayuki Obata, Kagayaki Kuroda   +5 more
wiley   +1 more source

Association between protein dose in the early and late acute phases of critical illness and time‐to‐discharge‐alive: A secondary analysis of a randomized clinical trial

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Research has sought to identify optimal protein doses during acute phases of critical illness to optimize outcomes. Methods A secondary analysis of the EFFORT Protein trial, which compared high vs usual protein (N = 1301). Only participants with 8 evaluable days of protein intake were included in our analysis.
Lauren E. Tweel, Rebecca Brody, Hamed Samavat, Andrew G. Day, Xuran Jiang, Laura Byham‐Gray, Jayshil Patel, Charlene Compher, Daren K. Heyland   +8 more
wiley   +1 more source

A chronopharmacological comparison of ciprofol and propofol: focus on sedation and side effects

Frontiers in Molecular Neuroscience
Propofol is a commonly used intravenous anesthetic in clinical practice, while ciprofol, a propofol derivative, also targets GABAA receptors with enhanced anesthetic potency.
Xuehan Li, Xinqing Yang, Chen Chen, Ziqing Yu, Houping Wang, Ruixue Liu, Jianrong He, Bin Shu, Guangyou Duan, Erquan Zhang, Dapeng Ju, He Huang   +11 more
doaj   +1 more source

Remifentanil–ketamine vs. propofol–ketamine for sedation in pediatric patients undergoing colonoscopy: A randomized clinical trial

Brazilian Journal of Anesthesiology, 2018
Background and objectives: Pediatric patients frequently require deep sedation or general anesthesia for colonoscopy. This study was designed to compare the sedative efficacy of remifentanil–ketamine combination with propofol–ketamine combination in ...
Feride Karacaer, Ebru Biricik, Murat Ilgınel, Çağatay Küçükbingöz, Mehmet Ağın, Gökhan Tümgör, Yasemin Güneş, Dilek Özcengiz   +7 more
doaj   +1 more source