Results 111 to 120 of about 149 (146)

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu   +7 more
wiley   +1 more source

Comparison effectiveness of topical analgesics with and without Entonox for esophagogastroduodenoscopy: A randomized controlled trial

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Abstract Objectives Esophagogastroduodenoscopy (EGD) is vital for diagnosing and treating upper gastrointestinal symptoms, but patient discomfort and anxiety can affect procedural outcomes. This study aimed to compare the effectiveness of topical analgesics with and without Entonox during EGD in terms of procedural success, patient tolerance, and ...
Papiroon Noitasaeng   +3 more
wiley   +1 more source

A pilot study on anti‐reflux mucoplasty with valve as novel endoscopic therapy for gastroesophageal reflux disease

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Abstract Background and aims Endoscopic anti‐reflux therapies like anti‐reflux mucosectomy (ARMS) and anti‐reflux mucosal ablation have shown efficacy for gastroesophageal reflux disease (GERD) in systematic reviews and meta‐analyses. Anti‐reflux mucoplasty (ARM‐P), a refinement of ARMS, incorporates immediate closure of the resection site to reduce ...
Kazuki Yamamoto   +11 more
wiley   +1 more source

Investigation of the actual implementation of “post‐sedation discharge criteria” and “time‐out” immediately before procedure in endoscopy: A nationwide survey study in Japan

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Post‐sedation discharge criteria for outpatient endoscopy and time‐out procedures immediately before endoscopic examinations are important for ensuring patient safety. This study used a web‐based questionnaire to survey the implementation status and current situation of these practices in Japan in 2024.
Atsushi Imagawa   +3 more
wiley   +1 more source

Impact of Non‐Anesthesiologist‐Administered Propofol Sedation for Outpatient Endoscopy in the Healthcare System

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Introduction Non‐anesthesiologist‐administered propofol (NAAP) sedation for outpatient endoscopy has proven to be safe. However, implementing NAAP in Western countries faces challenges, and propofol‐based sedation is still largely administered by anesthetists.
Francesco Vito Mandarino   +16 more
wiley   +1 more source

Drug co‐administration in anesthesia using event‐based MPC

open access: yesInternational Journal of Robust and Nonlinear Control, Volume 35, Issue 10, Page 4020-4042, 10 July 2025.
Abstract In this article, a predictive event‐based control architecture for multivariable drug infusion in the anesthesia process is presented. The control scheme considers a multiple‐input single‐output process, where the depth of hypnosis is the controlled variable and the infusion rates of propofol and remifentanil, which are co‐administered by ...
Andrzej Pawłowski   +4 more
wiley   +1 more source

Long‐Term Outcomes and Quality of Life of Children With Intracranial Ependymoma Treated With Pencil Beam Scanning Proton Therapy

open access: yesPediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT Background Ependymoma is a common brain tumor in children and adolescents. Adjuvant radiation therapy improves prognosis but carries potential toxicity risks, particularly for young patients. Proton therapy (PT) offers better conformal treatments and reduces dose exposure compared to traditional photon radiotherapy.
Eymeric Le Reun   +6 more
wiley   +1 more source

Case Report: Intestinal Diverticulum in a Golden Retriever

open access: yesVeterinary Medicine and Science, Volume 11, Issue 4, July 2025.
A 1‐year‐old female spayed Golden Retriever presented with a 2‐day history of vomiting and a chronic 4‐month history of intermittent diarrhoea. Owners elected to pursue exploratory laparotomy where a firm, tan, irregular structure was observed in the right caudal abdomen with a small adhesion to an adjacent loop of jejunum. The structure was removed en
Emily Eppler, Alyssa Motz
wiley   +1 more source

Intra‐Operative Cholangiography With Indocyanine Green Used to Assess Bile Duct Patency in a Dog With a Ruptured Gallbladder Mucocele

open access: yesVeterinary Medicine and Science, Volume 11, Issue 4, July 2025.
This case report describes the first veterinary use of indocyanine green (ICG) cholangiography to confirm common bile duct (CBD) patency in a dog with a ruptured gallbladder mucocele. The technique, commonly used in human laparoscopic hepatobiliary surgery, was successfully employed during cholecystectomy.
Yujin Kim, Sungin Lee
wiley   +1 more source

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