Robust photoregulation of GABA(A) receptors by allosteric modulation with a propofol analogue. [PDF]
, 2012 Photochemical switches represent a powerful method for improving pharmacological therapies and controlling cellular physiology. Here we report the photoregulation of GABA(A) receptors (GABA(A)Rs) by a derivative of propofol (2,6-diisopropylphenol), a ...
Bruzik, Karol S +8 more
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Safety and side effects of propofol in clinical practice - literature overview
Journal of Education, Health and Sport, 2023 Introduction and purpose Since people have been conducting surgeries to improve their health, they have always faced the problem of pain that these actions inevitably bring. Propofol as an anesetic is one of the solutions to these problems. Due to the
Maciej Lambach +9 more
doaj +1 more source
Anesthesiology, 2018 What We Already Know about This Topic Propofol may better preserve host defenses against cancer Whether cancer recurrence is less likely with propofol than volatile anesthesia remains unknown What This Article Tells Us That Is New The authors conducted a
Zhi-Fu Wu +9 more
semanticscholar +1 more source
Do Complexity Measures of Frontal EEG Distinguish Loss of Consciousness in Geriatric Patients Under Anesthesia? [PDF]
, 2018 While geriatric patients have a high likelihood of requiring anesthesia, they carry an increased risk for adverse cognitive outcomes from its use. Previous work suggests this could be mitigated by better intraoperative monitoring using indexes defined by
Caitlin M. Drover +8 more
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BMC Anesthesiology, 2018 BackgroundIt is unclear if anaesthesia maintenance with propofol is advantageous or beneficial over inhalational agents. This study is intended to compare the effects of propofol vs.
S. Schraag +7 more
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Cerebral and cardiovascular effects of analgesic doses of ketamine during a target controlled general anesthesia: a prospective randomized study [PDF]
, 2017 Introduction: Ketamine is increasingly being used in various pain settings. The purpose of this study was to assess the effect of an analgesic dose of ketamine in the bispectral index (BIS), spectral edge frequency (SEF-95), density spectral array (DSA),
Araujo, A. M. +3 more
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Inhalational or total intravenous anaesthesia: is total intravenous anaesthesia useful and are there economic benefits? [PDF]
, 2011 PURPOSE OF REVIEW: The comparison of inhalational and intravenous anaesthesia has been the subject of many controlled trials and meta-analyses. These reported diverse endpoints typically including measures of the speed and quality of induction of ...
Holmes, KA, Sneyd, JR
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Effect of Propofol on breast Cancer cell, the immune system, and patient outcome
BMC Anesthesiology, 2018 Breast cancer is the second leading cause of cancer death in women. Surgery is the first line of treatment for breast cancer. Retrospective clinical studies suggest that the type of anesthesia administered during oncological surgery may influence patient
Ru Li, Hengrui Liu, J. Dilger, Jun Lin
semanticscholar +1 more source
Effects of propofol in lipid-based emulsion and in microemulsion on the incidence of endothelial lesion in rabbits [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE: To compare the incidence of endothelial injury after single-dose or continuous propofol infusion in conventional lipid-based emulsion (LE) versus microemulsion (ME).
Cristian Durço Paço +8 more
doaj
Phase transitions in single neurons and neural populations: Critical slowing, anesthesia, and sleep cycles [PDF]
, 2010 The firing of an action potential by a biological neuron represents a dramatic transition from small-scale linear stochastics (subthreshold voltage fluctuations) to gross-scale nonlinear dynamics (birth of a 1-ms voltage spike). In populations of neurons
Sleigh, James W. +3 more
core +2 more sources