An environmentally relevant phthalate mixture impairs ovulatory prostaglandin and progesterone receptor pathways in human granulosa cells in vitro. [PDF]
Land KL, Xu H, Akin JW, Hannon PR.
europepmc +1 more source
Podocyte mPGES-2 Determines Renal Aging and Contributes to Senile Osteoporosis. [PDF]
Zhong D +16 more
europepmc +1 more source
Endogenous modulators in lung cancer. [PDF]
Patel N, Patel V, Surani S.
europepmc +1 more source
The Role of Prostaglandins as Major Inflammatory Mediators in Colorectal Cancer. [PDF]
Macia Guardado M +3 more
europepmc +1 more source
Potential Roles of Prostaglandins PGD2, PGJ2, and PGE2 in the Pathogenesis of Systemic Lupus Erythematosus. [PDF]
Xu T, Luo XM.
europepmc +1 more source
The inhibition of prostaglandin production during ovulation by exposure to a phthalate mixture is circumvented by cAMP analogue supplementation in a human granulosa cell model. [PDF]
Hannon PR +4 more
europepmc +1 more source
GLIS3, a novel regulator of eicosanoid gene expression and metabolism in normal kidney and polycystic kidney disease. [PDF]
Srivastava C +8 more
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Microsomal Prostaglandin E Synthase-1 in Osteoarthritis
Prostanoids (prostaglandins, prostacyclin and thromboxane) are locally acting lipid mediators. They are synthetized from arachidonic acid, which is released from cellular membrane phospholipids by phospholipase A2. Arachidonic acid is metabolised to prostaglandin G2 (PGG2), and onwards to prostaglandin H2 (PGH2), by cyclo-oxygenase (COX) enzymes.
openaire +1 more source
Geraniol Exerts Cytotoxic Effects in Red Cells Through Ca<sup>2+</sup> Elevation and Membrane Hyperpolarization: Attenuating Effects of COX/CK1α/Rac1 GTPase Inhibition. [PDF]
Alfhili MA, Alruwaili SH, Alsughayyir J.
europepmc +1 more source
Gut microbiota in chronic inflammation: the interplay with lipid mediators. [PDF]
Bao S, Yao C.
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