Prostaglandin-endoperoxide synthases

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Distribution of prostaglandin endoperoxide synthase and prostacyclin synthase in the late pregnant uterus

BJOG: An International Journal of Obstetrics & Gynaecology, 1986
Summary. Prostacyclin (PGI2) synthase and prostaglandin endoperoxide synthase (cyclo‐oxygenase; PGH synthase) were measured with specific immunoradiometric assays in myometrial microsomes from different areas of a primigravid uterus at 34 weeks gestation. PGH synthase concentrations increased significantly from fundus toward lower segment (P <0·005)
P, Moonen, G, Klok, M J, Keirse
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Prostaglandin endoperoxide synthase: why two isoforms?

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1996
Prostaglandin endoperoxide synthase-1 [prostaglandin G/H synthase-1 (PGHS-1)] and PGHS-2 are key enzymes in the conversion of arachidonic acid to prostaglandins and other eicosanoids. We refer to these isoforms as cyclooxygenase-1 (COX-1) and COX-2 in this review.
C S, Williams, R N, DuBois
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Characterization of a novel prostaglandin endoperoxide H synthase-1 transcript and examination of prostaglandin endoperoxide H synthase-1 expression.

2009
The prostaglandin endoperoxide H synthase (PGHS) enzyme plays a pivotal role in the prostanoid biosynthetic pathway because it catalyzes the formation of prostaglandin H2 (PGH2), the common precursor for prostanoids. The object of my research is to characterize a novel PGHS transcript and to examine the mechanisms that regulate PGHS-1 gene expression ...
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Prostaglandin-endoperoxide synthase

1994
Dietmar Schomburg, Dörte Stephan
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A model for the catalytic mechanism of prostaglandin endoperoxide synthase

Biochemical Society Transactions, 1993
H H, Ruf, U, Raab-Brill, C, Blau
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Prostaglandin Endoperoxide Synthases

William L. Smith, Lawrence J. Marnett
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Prostaglandin-Endoperoxide Synthase

2018
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REACTIONS OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE WITH NITRIC OXIDE AND PEROXYNITRITE*

Drug Metabolism Reviews, 1999
D C, Goodwin, L M, Landino, L J, Marnett
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Dynamics of different arachidonic acid orientations bound to prostaglandin endoperoxide synthases

European Journal of Medicinal Chemistry, 2011
Hugo Verli
exaly