Results 121 to 130 of about 4,137 (180)

Hic-5 promotes the progression of nonalcoholic steatohepatitis by regulating hepatocellular fatty acid metabolism through the PTEN/PGE2/EP4 axis. [PDF]

Mol Biomed
Huang Z, Tan P, Gu B, Liu S, Li H, Chen J, Ren B, Sun L, Wen J, Li Y, Fu W.   +10 more
europepmc   +1 more source

Reactive oxygen and nitrogen species: multifaceted regulators of ovarian activity†. [PDF]

Biol Reprod
Bezdíček J, Sekaninová J, Janků M, Makarevič A, Luhová L, Dujíčková L, Petřivalský M.   +6 more
europepmc   +1 more source

Utilising SNP Association Analysis as a Prospective Approach for Personalising Androgenetic Alopecia Treatment. [PDF]

Dermatol Ther (Heidelb)
Francès MP, Vila-Vecilla L, Russo V, Caetano Polonini H, de Souza GT.   +4 more
europepmc   +1 more source

Urinary prostaglandin D₂ and E₂ metabolites are elevated with disease severity in patients with Fukuyama congenital muscular dystrophy. [PDF]

Sci Rep
Ishigaki K, Takeuchi A, Taniguchi-Ikeda M, Sato T, Murakami T, Shichiji M, Ishiguro K, Kihara Y, Nagata S, Urade Y.   +9 more
europepmc   +1 more source

Comparative Analysis of Thromboxane B2 (TXB2) and Prostaglandin E2 (PGE2) Levels in the Gingival Crevicular Fluid (GCF) of Diabetic Patients With Chronic Periodontitis: An Enzyme Immunoassay Study. [PDF]

Cureus
Mahale AY, Agarwal S, Bansal R, Khan S, Goyel P, Chaubey A, Gupta S.   +6 more
europepmc   +1 more source

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Prostaglandin endoperoxide synthases-1 and -2

Journal of Lipid Mediators and Cell Signalling, 1995
Publisher Summary The chapter compares and contrasts the structural and kinetic properties of prostaglandin endoperoxide H synthase-1 (PGHS-1) and -2. It also discusses the description of the interactions of the two isozymes with nonsteroidal anti-inflammatory drugs (NSAIDs).
J C, Otto, W L, Smith
exaly   +3 more sources

Effects of flurbiprofen and flurbinitroxybutylester on prostaglandin endoperoxide synthases

European Journal of Pharmacology, 1996
The aim of our study was to evaluate the selectivity of flurbiprofen and flurbinitroxybutylester for inhibition of the cyclooxygenase activity of prostaglandin endoperoxide synthase-2 vs. prostaglandin endoperoxide synthase-1 in human blood monocytes and platelets, respectively.
Paola Patrignani
exaly   +4 more sources

The enzymology of prostaglandin endoperoxide H synthases-1 and -2

Prostaglandins and Other Lipid Mediators, 2002
We summarize the enzymological properties of prostaglandin endoperoxide H synthases (PGHs)-1 and -2, the enzymes that catalyze the committed step in prostaglandin biosynthesis. These isoenzymes are closely related structurally and mechanistically.
William L, Smith, Inseok, Song
exaly   +3 more sources

The structures of prostaglandin endoperoxide H synthases-1 and -2

Prostaglandins and Other Lipid Mediators, 2002
Despite the marked differences in their physiological roles, the structures and catalytic functions of the prostaglandin H2 endoperoxide synthases-1 and -2 (PGHS-1 and -2) are almost completely identical. These integral membrane proteins catalyze the conversion of arachidonic acid to PGG2 and finally to PGH2.
R Michael Garavito, Michael Malkowski
exaly   +3 more sources