Results 121 to 130 of about 64,031 (206)

The effects of endocrine‐disrupting chemicals on ovarian‐ and ovulation‐related fertility outcomes

open access: yesMolecular Reproduction and Development, Volume 89, Issue 12, Page 608-631, December 2022., 2022
Abstract Exposure to endocrine‐disrupting chemicals (EDCs) is unavoidable, which represents a public health concern given the ability of EDCs to target the ovary. However, there is a large gap in the knowledge about the impact of EDCs on ovarian function, including the process of ovulation.
Katie L. Land   +3 more
wiley   +1 more source

Chain length specificity for activation of cPLA2α by C1P: use of the dodecane delivery system to determine lipid-specific effects

open access: yesJournal of Lipid Research, 2009
Previously, our laboratory demonstrated that ceramide-1-phosphate (C1P) specifically activated group IVA cytosolic phospholipase A2 (cPLA2α) in vitro. In this study, we investigated the chain length specificity of this interaction. C1P with an acyl-chain
Dayanjan S. Wijesinghe   +8 more
doaj  

The Isolation of Prostaglandin E from Sheep Prostate Glands. [PDF]

open access: bronze, 1960
Sune Bergström   +4 more
openalex   +1 more source

Total Synthesis of Ectocarpin A

open access: yesEuropean Journal of Organic Chemistry, Accepted Article.
A total enantioselective synthesis of Ectocarpin A, an oxylipin identified through the first hydroperoxide bicyclase activity of CYP5164A3 in brown algae, has been successfully completed in 12 steps starting from tetrahydro‐1H‐cyclopentafuranone.
Alexandre Guy   +2 more
wiley   +1 more source

Developmental pharmacokinetics of indomethacin in preterm neonates: Severely decreased drug clearance in the first week of life

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 12, Issue 1, Page 110-121, January 2023., 2023
Abstract Indomethacin is used commonly in preterm neonates for the prevention of intracranial hemorrhage and closure of an abnormally open cardiac vessel. Due to biomedical advances, the infants who receive this drug in the neonatal intensive care unit setting have become younger, smaller, and less mature (more preterm) at the time of treatment.
Wojciech Krzyzanski   +7 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Dihydroartemisinin inhibits melanoma migration and metastasis by affecting angiogenesis

open access: yesPhytotherapy Research, EarlyView., 2023
Abstract Tumor angiogenesis is critical for tumor metastasis by providing oxygen, nutrients, and metastatic pathways. As a potential anti‐angiogenic agent, Dihydroartemisinin (DHA) can effectively inhibit tumor metastasis. However, the mechanism how it regulates angiogenesis to affect tumor metastasis has not been fully clarified.
Zhaoxiang Li   +8 more
wiley   +1 more source

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