Results 31 to 40 of about 371,177 (386)

Transitioning Stable Patients with Pulmonary Arterial Hypertension from Parenteral Prostanoids to Oral Selexipag

open access: yesBiomedicine Hub, 2022
Introduction: Parenteral prostanoids are the most potent therapies for pulmonary arterial hypertension (PAH) but are associated with complications and lifestyle limitations.
Colin Hinkamp   +4 more
doaj   +1 more source

Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes.

open access: yesJournal of Clinical Investigation, 2001
Virtually every organism has evolved mechanisms by which, upon stimulation, lipids are released from plasma membranes and metabolized into mediators capable of changing cellular physiology.
S. Tilley, T. Coffman, B. Koller
semanticscholar   +1 more source

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins[S]

open access: yesJournal of Lipid Research, 2010
Exosomes are bioactive vesicles released from multivesicular bodies (MVB) by intact cells and participate in intercellular signaling. We investigated the presence of lipid-related proteins and bioactive lipids in RBL-2H3 exosomes.
C. Subra   +11 more
semanticscholar   +1 more source

Aspirin inhibits the acute venodilator response to furosemide in patients with chronic heart failure [PDF]

open access: yes, 2001
OBJECTIVES: We sought to determine the effect of aspirin on the venodilator effect of furosemide in patients with chronic heart failure (CHF) BACKGROUND: Furosemide has an acute venodilator effect preceding its diuretic action, which is blocked
Andrew P Davie   +33 more
core   +1 more source

Prostaglandins for preventing postpartum haemorrhage.

open access: yesCochrane Database of Systematic Reviews, 2012
BACKGROUND Prostaglandins have mainly been used for postpartum haemorrhage (PPH) when other measures fail. Misoprostol, a new and inexpensive prostaglandin E1 analogue, has been suggested as an alternative for routine management of the third stage of ...
Özge Tunçalp   +2 more
semanticscholar   +1 more source

Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids. [PDF]

open access: yes, 2016
The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood.
Currais, Antonio   +5 more
core   +2 more sources

Prostaglandins and anti-prostaglandins in pathogenesis and treatment of primary dysmenorrhea [PDF]

open access: yesГинекология, 2017
The article deals with modern theories of the pathogenesis of dysmenorrhea. A special place is given to prostaglandin, an anti-prostaglandin theory. As a therapy for dysmenorrhea, the group of prostaglandin-synthetase inhibitors is considered in detail ...
E A Mezhevitinova, V N Prilepskaya
doaj  

Celecoxib Improves Host Defense through Prostaglandin Inhibition during Histoplasma capsulatum Infection

open access: yesMediators of Inflammation, 2013
Prostaglandins act as mediators of inflammation and, similar to cytokines, function as immune modulators during innate and adaptive immune responses. Therefore, using a pharmacological inhibitor, celecoxib, we investigated the role of prostaglandins in ...
Priscilla Aparecida Tartari Pereira   +8 more
doaj   +1 more source

Prostaglandin E2 and F2alpha Modulate Urinary Bladder Urothelium, Lamina Propria and Detrusor Contractility via the FP Receptor

open access: yesFrontiers in Physiology, 2020
Current pharmacological treatment options for many bladder contractile dysfunctions are not suitable for all patients, thereby bringing interest to the investigation of therapies that target a combination of receptors.
Zane Stromberga   +2 more
doaj   +1 more source

NaCl transport stimulates prostaglandin release in cultured renal epithelial (MDCK) cells [PDF]

open access: yes, 1986
Prostaglandins (PGs) can modulate a variety of renal functions, including Na+ and Cl- reabsorption. However, it is not known if a direct interdependence exists between PG synthesis and transport activity. The present study was done to find out whether or
Bauer, C.   +3 more
core   +1 more source

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