Results 41 to 50 of about 243,841 (348)
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source
THE EFFICASY OF STRUCTUM (CHONDROITIN SULFATE) ON BIOENERGETIC CHARACTERISTICS OF OA SYNOVIAL FLUID
Clinical and laboratory study was carried out including 30 pts with definite diagnosis of osteoarthritis (OA ) of knee joint. The effect of chondroitin sulfate (Structum) on basic bio-energetic indices of synovial fluid was studied.
V I Shishkin +2 more
doaj +1 more source
FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases [PDF]
Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role in several physiological processes and their concentration in phospholipids has been associated with several complex diseases, such as atopic disease.
Heinrich, Joachim +3 more
core +1 more source
Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan +8 more
wiley +1 more source
Design rules are presented to control intestinal organoid polarity in fully synthetic hydrogels. The laminin‐derived IKVAV sequence is crucial to obtain correct intestinal organoid polarity. Increasing hydrogel dynamics further supports the growth of correctly polarized intestinal organoids, while a bulk level of stiffness (G’ ≈ 0.7 kPa) is crucial to ...
Laura Rijns +10 more
wiley +1 more source
Cervical Ripening in The Netherlands: A Survey
Objective. We aim to investigate methods and use of cervical ripening in women without and with a prior cesarean delivery in The Netherlands. Methods. In 2010, we conducted a postal survey in all Dutch hospitals with a labor ward.
Claartje M. A. Huisman +4 more
doaj +1 more source
Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]
Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM +3 more
core
cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-beta-Induced Synapse Damage [PDF]
A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Bate, C, Williams, A
core +2 more sources
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro +4 more
wiley +1 more source
Primary dysmenorrhea: strategy and tactics of treatment [PDF]
The article summarizes the results of numerous randomized studies and structured the approach to the tactics of managing patients with primary dysmenorrhea.
Yu E Dobrokhotova +2 more
doaj +1 more source

