Results 41 to 50 of about 371,177 (386)

Identification of Prostaglandin Pathway in Dinoflagellates by Transcriptome Data Mining

open access: yesMarine Drugs, 2020
Dinoflagellates, a major class of marine eukaryote microalgae composing the phytoplankton, are widely recognised as producers of a large variety of toxic molecules, particularly neurotoxins, which can also act as potent bioactive pharmacological ...
Valeria Di Dato   +2 more
doaj   +1 more source

The American Catholic: Contraception and Abortion [PDF]

open access: yes, 1971
Dr. FitzGerald looks at the position in which social and environmental pressures, widespread contraception and the new therapeutic range of the prostaglandins have placed the American ...
FitzGerald, James A.
core   +1 more source

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]

open access: yes, 2017
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P   +11 more
core   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Influence of Natural Honey on Biochemical and Hematological Variables in AIDS: A case study

open access: yesThe Scientific World Journal, 2006
Honey lowers prostaglandins and elevates nitric oxide (NO) in various biological fluids in normal persons. NO and prostaglandin play a role in pathogenesis of AIDS.
Noori S. Al-Waili   +3 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

METHOD FOR MODULATING EICOSANOID MEDIATED IMMUNE RESPONSES IN ARTHROPODS [PDF]

open access: yes, 2000
The invention is directed to compositions which alter the health of invertebrate organisms by affecting eicosanoid mediated immune responses, and methods of using the compositions.
Stanley, David W.
core   +1 more source

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

open access: yesFEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos   +3 more
wiley   +1 more source

Multi‐omics analyses reveal the interaction between colonic microbiota and host in Min and Yorkshire pigs

open access: yesAnimal Research and One Health, EarlyView., 2023
In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang   +6 more
wiley   +1 more source

Localization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells [PDF]

open access: yes, 2009
When the succinate receptor (SUCNR1) is activated in the afferent arterioles of the glomerulus it increases renin release and induces hypertension.
Deen   +37 more
core   +1 more source

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